Is the offspring’s DNA methylome a possible mechanism through which direct and indirect genetic effects act? Yes! In this new Netherlands Twin Register preprint, we found 51 offspring CpGs related to parental or offspring PGSs for schizophrenia, EA, BMI & height. 1/4

John Burn-Murdoch Liz M If you're interested in Dutch cohort data, there's 20+ years of mental health and behavioural problem data from Netherlands Twin Register (overview here: pubmed.ncbi.nlm.nih.gov/31666148/), as well as the Generation R cohort (ncbi.nlm.nih.gov/pmc/articles/P…).

New team wellbeing publication! 🎉 
We (Dirk Pelt Meike Bartels Netherlands Twin Register ) investigated the stability and change in wellbeing across the lifespan (5 to 75+ years).
doi.org/10.1017/S00332…

Out now! The profile article of our BIObanks Netherlands Internet Collaboration ( #BIONIC ) project, a #GWAS dataset of >66,000 🇳🇱 subjects to study the genetic base of #Depression . Big shoutout to Floris Huider for his great work on the data and the paper: bit.ly/3vgIH6u

The cohort profile of our BIObanks Netherlands Internet Collaboration ( #BIONIC ) has been published! We describe the #GWAS dataset of >66,000 Dutch subjects to study the genetic basis of #Depression . doi.org/10.1017/thg.20…. A huge thank you to the cohorts that have contributed!

New preprint by Bodine Gonggrijp
Netherlands Twin Register
Negative Life Events and Epigenetic Ageing: a Study in the Netherlands Twin Register biorxiv.org/content/10.110…

Thanks to all collaborators (Dr Elsje van Bergen and Twitterless others), and to the twins participating in the Netherlands Twin Register Netherlands Twin Register !

And the best poster in statistical genetics goes to...🥁 Charlotte Pahnke!🏆 According to the jury, for her wonderful work on methods development, integrating family models with measured DNA, to estimate gene-environment correlation. 👏
IBG Netherlands Twin Register Josefina Bernardo

3/4 🎬Check out an example of IV-CLPM in action! 🚬🍺 Using polygenic scores, explores causation between #smoking & #alcohol use in Netherlands Twin Register. Results reveal proximal effects of alcohol on smoking, along with lagged reverse effects of smoking on alcohol. #CausalInference

🚨📝We have updated our preprint 'Comorbidity and causality among #ADHD #dyslexia & #dyscalculia '! We have now equated prevalences (<10%). Interested in #ReadingFluency and #spelling disorders? See supplements. Kees-Jan Kan Dr. Sara A. Hart Netherlands Twin Register psyarxiv.com/epzgy

Last week to apply for these PhD and Postdoc positions!
Netherlands Twin Register Bruno Sauce Wonuola Akingbuwa Dr. Tinca Polderman Dennis van 't Ent

Last class of their MSc programme vu.nl/genes #rmGBH ! Eco de Geus and I thoroughly enjoyed teaching this bright group. Now they're off to Netherlands Twin Register's (inter)national collaborators for their thesis projects.🎓🧳✨ All the best! #GeneEnvironment

Ingrid Szilagyi (👇right; from MaxPlanck-Psycholinguistics) visited us #TwinWise Netherlands Twin Register to present her pre-registered study on polygenic scores predicting language skills osf.io/nbv7a. Free test battery for adult Dutch speakers mpi.nl/idlas-nl. Enjoyed discussing 🗣️💬🧬!

Spread the word. Amsterdam is fun!
Genetics Network Amsterdam Netherlands Twin Register

Check out these exciting new opportunities! All 4 year positions with amazing colleagues!

Fiona Hagenbeek Netherlands Twin Register Jenny van Dongen Center for Open Science Genetic interpretations of twin studies are based on the assumption that MZ and DZ environments are 'equal.' As critics have argued for 90+ years, this assumption is clearly false, leading to a false set of conclusions. The review makes no mention of this key assumption. #EEAtwins

Vrije Universiteit Amsterdam Dr Elsje van Bergen Netherlands Twin Register Gut voor zo’n conclusie moet je echt doorgeleerd hebben. 🤪🤪

Dr Elsje van Bergen Bruno Sauce Britt Min Josefina Bernardo Prowise Global Prowise Netherlands Twin Register Intriguing project, Dr. van Bergen! Curious, how do you see AI tools influencing educational equality in the future?

New paper by Anna Niehues Fiona Hagenbeek Netherlands Twin Register X-omics
Multi-omics data analysis workflow packaged as a FAIR Digital Object academic.oup.com/gigascience/ar…

11/11 Also a big thanks to participants of Lifelines, LLS, RS, Netherlands Twin Register, CODAM, PAN, ROSMAP, Mayo, MSBB, CMC, GTEx Portal, NABEC, Target ALS, UCLA ASD, Bipseq, Braineac, BrainGVEx, LIBD, the tissue donors and families, and dataset-associated researchers.