EUbOPEN partner @AlessioCiulli, pioneers a molecule that targets a previously 'undruggable' protein class! By ingeniously masking the molecule, it can enter cells paving the way for innovative disease treatments.
nature.com/articles/s4146…
@IMI Centre for Targeted Protein Degradation

In the last #20yearsSGC , we're thrilled to be part of the EUbOPEN consortium, an endeavor dedicated to developing high-quality chemical tool compounds for 1,000 proteins. Over the past 3 years, our collective efforts have yielded remarkable achievements.

The 2nd EUbOPEN annual meeting was successfully held earlier this week. Among affiliated partners, SGC showcased a strong presence, by sharing updates on our progress toward the consortium's goal of generating chemical modulators for the entire druggable proteome.

Register now for Target 2035's upcoming webinar on February 21 and learn all you need for XChem, a dedicated platform for crystallographic fragment screening. Daren Fearon Diamond Light Source Lizbe Koekemoer Centre for Medicines Discovery @EubOPEN bit.ly/3jBYlU6

🙌 EUbOPEN is fully committed to #OpenScience and aims to publish all its generated data open and fully #accessible to everyone.
Read our case study 📄 on EUbOPEN to find out our collaboration on making data #FAIR : fairplus-project.eu/news/eubopen-c…

The Donated Chemical Probes set is now available in the latest Probes & Drugs update: probes-drugs.org/news#45

Probes from Boehringer Ingelheim's #opnME , Chemical Probes Portal and the EUbOPEN chemogenomics set are also included.

#OpenScience

Don't miss your opportunity to take part in the second #CACHEChallenge ! The target is the NSP13 helicase of #SARSCoV2 . Submit your application to join the CACHE competition. Apply today! bit.ly/3bqngFW
#DrugDiscovery #OpenScience #Target2035

Beautiful!

cc: EUbOPEN

RT
EUbOPEN #trainees #phdstudent #chemicalbiology

Happy to share that they liked my flash talk enough to give me a prize at the #SeedpodsDay ! Life pro tip, wear a baby bump as a good luck charm!

This Tuesday JUNE 14 10AM EDT/4PM CEST Target2035 Webinar: Towards Autonomous Bioactive Molecular Discovery! Register NOW target2035.net/upcoming-webin…

cc: EUbOPEN

It's here: you can now download all the data on the Chemical Probes Portal! Use our new feature to download the full dataset, choose individual chemical probes or filter by protein target, target family, expert rating etc.
Find out more: chemicalprobes.org/news/new-featu…

We're seeking inhibitors of #PLCzeta1 towards new, inexpensive, non-hormonal female contraceptives. You'll work with other target champions across the worldwide Structural Genomics Consortium (SGC) - a very strong, collaborative team funded by the Gates Foundation. #globalhealth 2/3

Groundbreaking work from Cheryl Arrowsmith, Structural Genomics Consortium (SGC) team U of T Research, Princess Margaret Cancer Centre Research and research partners released today in Nature Chemical Biology reveals MS023 induces #antitumor activity for #triplenegativebreastcancer .
Read more here: go.nature.com/3wsL5DH

Interested in a new challenge? Check out this role for a Senior Scientist and Programme Leader at Centre for Medicines Discovery cmd.ox.ac.uk/jobs#157818

Register now for the next Target 2035 webinar!

This is a great webinar series! FragileNucleosome also have YouTube channel youtube.com/channel/UCAnaB….

cc: EUbOPEN

Register now for the next Target 2035 webinar!

A new drugit.org game is running. KLHDC2 is a substrate receptor of the CRL2 E3 complex and recognizes C-end degrons. Support future PROTAC development and give it a try! Open Science EUbOPEN Structural Genomics Consortium (SGC) Chemical Probes Portal University of Oxford Vanderbilt University Boehringer Ingelheim