Join Prof Lenka Munoz and colleagues for the #Target2035 webinar on June 7th at 5pm AEST. This global initiative by SGC, ICR, Oxford, Karolinska & Uni Toronto researchers aims to develop chemical probes for the entire proteome by 2035. Register here: bit.ly/42d2qP2
The next #openscience online meeting of the #READDI #antiviral #drugdiscovery project vs #SARSCoV -2 #Nsp13 is Monday at 5pm UK time. github.com/StructuralGeno…… All welcome.
Target 2035 Structural Genomics Consortium (SGC) at
An #openscience project needing community help from computational modellers. WDR91 for host-directed antivirals. We've binders + xstal structure. We need to understand the data, particularly the matched pairs. github.com/StructuralGeno… Structural Genomics Consortium (SGC) Target 2035 UCL Faculty of Life Sciences
#GetInvolved with #openscience
We've #Fragments bound at #SARSCoV2 Nsp10/Nsp14 interface & need to grow/merge/link. Details at lnkd.in/eKHiiNQH Live & at Fragalysis lnkd.in/eNzEVAPZ. We can buy/make/measure.
Structural Genomics Consortium (SGC)
UCL
Matthew Todd Target 2035
#antiviral
Inspiring Leiden Early Drug Discovery & Development (LED3) Lecture by Cheryl Arrowsmith from Structural Genomics Consortium (SGC) #target2035 . She talked about her group's research into identifying new therapeutic opportunities in the proteome using chemical probes. Great insights into protein methyltransferases. thesgc.org/chemical-probes
The goal of Target 2035 is to provide chemical probes for every member of the human proteome. With HSD17B13 inhibitor #BI3231 another step is taken. Nice hit-to-lead work in increasing inhibitor efficiency & keeping good properties ACS Publications Bio & Med Chem Content Lars Wortmann pubs.acs.org/doi/10.1021/ac…
British Columbia ramps up its goal for zero-emissions vehicles with an aspiration to reach complete sales of these vehicles by year two thousand thirty-five. #BritishColumbiaZeroEmissions #Target2035 #VehicleSales100Percent spanglish.ca/blogs/canada/b…
Awesome to host Cheryl Arrowsmith from Structural Genomics Consortium (SGC) Toronto for a talk at UCL School of Pharmacy and UCL Chemistry on Target 2035 and other projects, including this very cool new NSD2 degrader: pubs.acs.org/doi/abs/10.102…
Lovely talk yesterday at UCL School of Pharmacy from Tim Willson giving overview of Structural Genomics Consortium (SGC) UNC Pharmacy research in drugging understudied proteins. Target 2035 Included v nice story of basic research --> open probe --> obeticholic acid/Ocaliva helping patients.
Paul Workman The ICR kicked off the Target 2035 webinar with background about why we need high quality #ChemicalProbes and protein inhibitors, and the problems recognised by the chemical biology community.
Almost in time for the 20 years anniversary of Structural Genomics Consortium (SGC): Target 2035 - an editorial about private sector contributions to the quest to drug every protein in the human genome. pubs.rsc.org/en/content/art… #OpenScience RSC Medicinal Chemistry Target 2035 The SGC Frankfurt
Don't miss out! CACHE will reveal the most efficient computational method for hit-finding and guide future technological improvement. Complete your application today and join the challenge!
cache-challenge.org/application/19…
#cachechallenge #openscience #computationalmethod #target2035
Today's SARS-CoV-2 #nsp13 #helicase meeting is at 5pm London time. All welcome #openscience github.com/StructuralGeno… Structural Genomics Consortium (SGC) #target2035 #READDI #medchem #antivirals
I'm a big fan of this beautiful nod to research transparency by the Zayed Centre at GOSHCharity. Now I wonder if there are some actual #openscience projects we could do... Structural Genomics Consortium (SGC) M4K Pharma Target 2035
Several #openscience projects in the lab are nicely poised for community inputs. Here's a peach. One of the Structural Genomics Consortium (SGC) Open Chemistry Networks needs some simple ureas. You make, we test. Protocols available. github.com/StructuralGeno… Target 2035 UCL Faculty of Life Sciences
Anke Mueller-Fahrnow opening proceedings at the Structural Genomics Consortium (SGC) Target 2035 meeting in Frankfurt. 'From pilot phase to operations'. 24 companies, lots of funders (incl Wellcome, Medical Research Council) very good crowd. Emphasis on exptl hit finding driving better #AI #MachineLearning
...and here's aled edwards closing the 20y celebration of Structural Genomics Consortium (SGC) though, as he says, he's a 'look forward kind of a guy'. Stay tuned for the Euro version of this celebration in Sept. #target2035 The SGC Frankfurt #openscience
📢This month's issue features an update on the private sector contributions to Target 2035 from Suzanne Ackloo, Cheryl Arrowsmith & co⬇
pubs.rsc.org/en/content/art…
#Target2035 is an open science movement to develop pharmacological tools for all human proteins by 2035👏
