Plasma EVs as window to the brain- #ExtracellularVesicles as biomarkers of neurodegenerative disease Dima Ter-Ovanesyan #ISEV2024 ISEV

At the #biomarkers session Dmitry Ter-Ovanesyan introducing his approach for #Extracellularvesicles isolation from neurons
#ISEV2024 Day4

need a point of care test for the virus, because every one of those biomarkers works for another one also

Walter J. Koroshetz #MECFS costs the economy $362 Billion dollars a year but you
*ignore patient advocates
* only fund #MECFS 13 Million dollars a year
* Misuse #MECFS biomedical funding for 'other projects'
* Psychologize #MECFS patients with your MDD hypotheses and psychosomatic bullshit

all: your age is your time since birth

you can age better or worse but you are aging

you can't reverse your age but you can improve aging trajectory

noone can quantify your biological age w correlative biomarkers & those scores don't allow anyone to say they reversed their age

ฟังเลกเชอร์วนๆไปจ้าาา .. ยารักษาในระยะ MCI รอเข้าไทย แต่ต้องมี lab ตรวจ AD biomarkers หรือ PET amyloid scan ด้วย คือต้องตรวจพบ amyloid ในสมองถึงจะให้ยา anti-amyloid จ้าาา

Walter J. Koroshetz *You ignore #MECFS biomedical hypotheses like viral persistence, viral reactivation, autoimmunity, T cell exhaustion
*You deny funding for #MECFS biomarkers like the Nanoneedle and mistreat our researchers like Dr. Ron W Davis
* You ignore the #MECFS patient voice and demands

Biomarkers of #mitochondrial dysfunction in #autism spectrum disorder: A systematic review and meta-analysis
sciencedirect.com/science/articl…

#Biomarkers #HeartFailure

Immunosciences lab research recently studied 90 #LongCovid patients & shown they have biomarkers of SARS2 viral persistence, HHV-6 reactivation, autoimmune reactions to activin-A, & activated immune oxidative pathways. These markers showed 80% significant predictive accuracy.

#Myalgicencephalomyelitis /chronic fatigue syndrome (ME/CFS) Awareness Day
Has 1 objective marker and 4 diagnostic blood tests in development
Maybe what you think you know about ME/CFS is wrong...
May 12th #MeasureMECFS

Can we utilise Brain #ExtracellularVesicles #brainEV as biomarkers of Brain health -Lesley Cheng #ISEV2024 ISEV Communications Team

it's amazing seeing people interacting & talking about me/cfs today 🥹
research has found biological differences in cells of people with cfs, but we still don't have any conclusive biomarkers (meaning we can't test/chemically treat cfs yet)

awareness -> research -> more studies

Distinct pre-clinical serological and biomarker profiles of patients with B2/B3 Crohn's disease, up to 6 years before diagnosis.

- increased antimicrobial antibodies (ASCA, anti flagellin)
- increased innate & adaptive immunity, fibrosis biomarkers

Application of #Extracellularvesicles glycosylation patterns as #biomarkers for gastric cancer presented by Li Min
#ISEV2024 Day3

Walter J. Koroshetz The best way to identify potential treatments for #MECFS is to identify, fund, and approve #MECFS biomarkers and to advance only testable, measurable, falsifiable hypotheses
Instead #NIH ignores #MECFS biomedical findings, and denies research grants for #MECFS biomarkers

Aging-US recently #published this #researchpaper in Volume 16, Issue 4: “Associations of prenatal one-carbon metabolism nutrients and metals with epigenetic aging biomarkers at birth and in childhood in a US cohort.' Stanford Epidemiology & Population Health

doi.org/10.18632/aging…

#aging #aging short

SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir

✅ Just Accepted
🔗 bit.ly/4dqKdEu

'Biomarkers in Clinical Trials'
In this session, we will explore the vital importance of biomarkers in clinical trials, highlighting their role in monitoring glomerular disease progression, treatment response, and patient outcomes. Experts will cover recent advances in…

while all fruits are healthy, berries are easily the only S tier fruit

the amount needed to drastically change biomarkers in the short term is only ~100 grams, the size usually sold at supermarkets

apples, watermelon, are D tier, basically memefruits, and isnt that healthy