Say hello to the first group of Investigators at #CZBiohubNY ! Check out their projects to enable Biohub New York to harness the power of immune cells for early detection of cancer and neurodegenerative diseases.

Learn more ➡️
czbiohub.org/ny/

The first 7 #CZBiohubNY Investigators aim to build new tools to characterize + bioengineer immune cells that will eventually detect disease earlier bit.ly/4dDKunl

“Humans have a hard time visualizing something in 20,000 dimensional space, So we need the help of computers.”

In the newest episode of Moira Gunn, Stephen Quake spoke with Moira Gunn about how we’re using #AI to create predictive models of cells bit.ly/4acqpSn

Physics 🤝 Biology

#CZBiohubSF Investigator Hawa Thiam is designing new ways to experimentally replicate the physical forces cells encounter in the body bit.ly/3vbEIbo

By employing very high-resolution CT scans of entire human kidneys, @Sarahteichmann1 + HiP-CT team are linking our knowledge of molecular changes to an imaging modality. It is a step towards linking cell atlas data to clinical imaging

In this @nature piece, Theodoris Lab says it took 2 months to manually aggregate the 30M+ #SingleCell datasets that initially trained their deep-learning model, Geneformer.

We built CZ #CellxGene so that now this work can be done in minutes. Read more ⤵️ nature.com/articles/d4158…

Open research + AI = the power to transform scientific work. That's why we're launching an RFI with @sloanfoundation to learn more about existing applications of AI that align with open research principles.

📫 Submit your ideas by May 30 bit.ly/49ZUR26

As neuroscience uncovers more of the molecular & cellular mechanisms of neurodegeneration, new questions emerge about how they affect neuronal networks.

Sabine Krabbe is uncovering how local pathology impacts neuronal function in the amygdala 🧠

At NYAS our co-founder Priscilla Chan shared the latest on the #AI models we’re training to help researchers better understand the molecular underpinnings of healthy + diseased cells

.@Sarahteichmann1 + the HiP-CT team are #ImagingTheFuture by mapping #SingleCell gene expression in the 3D tissue + organ morphology context to understand how cells interact and function within tissues and as whole organs

Mitochondria serve as energy supplies near neuronal synapses. Using their novel spine + mitochondrial ATP reporters, Vidhya Rangaraju, PhD and team are measuring synaptic mitochondrial function in vivo & in human iPSCs to understand mitochondrial phenotypes in #ALS

#ALS AwarenessMonth

Are you developing tools for #AI enabled research practices that also promote open research? We want to hear from you! Submit your ideas to our RFI so we can build a more effective scientific community together ▶️ bit.ly/49ZUR26

“That’s approximately 11-and-a-half million more cells than we would typically run in a single-cell experiment.” - Tim Triche, Jr. (@timtriche.bsky) on how CZ #CellxGene helped scale + accelerate his lab’s work on immune cells.

More on this & what’s next in nature go.nature.com/3WiFjmM

In-person registration has now sold out, but virtual tickets are still available for this #AI event!🙌 Join us on May 2 to explore the applications of AI in rare diseases, cell engineering, & more. Presented by the Academy & Chan Zuckerberg Initiative. Register now: bit.nyas.org/3Vw7k9Y

Never before have so many opportunities existed for training, capacity building, collaboration & career development in bioimaging. Comunidad Mexicana de BioImagen is #ImagingTheFuture by expanding access to bioimaging in Mexico

Chan Zuckerberg CELL by GENE Discover aims to be a one-stop shop for single-cell RNA sequencing data storage, access and analysis go.nature.com/4bfU7Xv

Gus Hart + his team are accelerating research by:
💡 Bringing in new ideas from the broader #AI imaging community
🖥️ Providing public software and annotated datasets to aid newcomers
📸 Expanding the number of scientists applying AI to cryotomography

Thanks to Chan Zuckerberg Biohub Network’s collaborative model, investigators from #CZBiohubSF + UC Berkeley use optogenetics & 3D holographms for advanced brain communication. This project showcases the power of partnership in driving scientific discovery bit.ly/493i5DO

Fluorescent proteins like GFP have revolutionized optical microscopy. Philipp S. Erdmann + Roman Jerala aim to create similarly helpful tags for #cryoET using protein origami nanostructures, which could open up new possibilities for visualizing small & disordered protein structures