Our paper describing the structure of the membrane enzyme performing the Meinwald reaction, Styrene Oxide Isomerise, is out in Nature Chemistry 👇
nature.com/articles/s4155…

Peter-Leon Hagedoorn Korkhov Lab PSI Paul Scherrer Institut NUS ETH Zurich D-BIOL @ ETH Zurich Ruhr-Universität Bochum TU Delft Here is PSI press release for our article, where Xiaodan and Richard discuss potential of SOI as bionanomachine for green chemistry and development of circular economy psi.ch/en/media/our-r…

The Faculty of Biology and Biotechnology of Ruhr-Universität Bochum is looking for an Academic Senior Counsillor for the development of the mass spectrometry facility. If you are interested 👇👇
jobs.ruhr-uni-bochum.de/jobposting/890…

Biotechnology: How to Make Ubiquitous Plastics Biodegradable - news.rub.de/english/press-… via Ruhr-Universität Bochum

The enzyme styrene oxide isomerase from bacteria efficiently catalyses the Meinwald reaction, an important chemical reaction that in industry can only be carried out with high energy input and low product yields. brnw.ch/21wJL23 Korkhov Lab

Mit der Aufklärung der Funktion eines bestimmten Bakterien-Enzyms ist der Weg zum biotechnologischen Abbau von Styrol geebnet. #Biotechnologie news.rub.de/wissenschaft/2…

Amazing to see our newest contribution in Nature Chemistry ... the styrene oxide isomerase is small but powerful #heme #enzyme as well as a #membraneprotein ! A great international collaboration! Thx to all the team members being involved!

nature.com/articles/s4155…

Structural basis of the Meinwald
rearrangement catalysed by styrene
oxide isomerase; B. Khanppnavar, J. P. S. Choo Peter-Leon Hagedoorn G. Smolentsev, S. Štefanić Selvapravin Kumaran Dirk Tischler F. K. Winkler, V. M. Korkhov, Z. Li, R. A. Kammerer 1 & X. Li

#Membranebound #styreneoxideisomerase #Meinwaldrearrangemen #epoxide #cascadereactions
#electronparamagneticresonancespectroscopy

doi.org/10.1038/s41557…

Want to know how nature performs “Stereospecific” Meinwald rearrangement reaction? Check out our paper Nature Chemistry, where we study the Styrene Oxide Isomerase (SOI), the one of the only two enzymes known to catalyzes this unique reaction in nature.
nature.com/articles/s4155…

It has been a pleasure to collaborate with Andrés R. Alcántara in the preparation of the book 'Biocatalysis in Asymmetric Synthesis' from Elsevier. It took some time but in the end it has been done.
shop.elsevier.com/books/biocatal…

Just finishing your #PhD and wondering if the #DFG ’s Walter Benjamin Programme is a #fundingoption for your next step in academia? Find out in our digital #infotalk on 16/5 (4 p.m., in English). More info, upcoming talks and link to the video conference: ➡️dfg.de/en/research-fu…

Our microbiotech : The Tischler Lab group picture is updated for the coming events, a great team 😉 get in contact we will be attending many conferences this summer! #actinobacteria #enzymology #biotechnology #biotransformation

Standpunkt: KI als Chance und Herausforderung in der #Biotechnologie - news.rub.de/leute/2024-05-… via Ruhr-Universität Bochum

Some thoughts 💬 from a task force of #academia and #industry connected via #biotransformation group of DECHEMA e.V. and VAAM - Vereinigung f. Allg. u. Ang. Mikrobiologie

#biotechnology

The Development and Opportunities of Predictive Biotechnology - Nestl - ChemBioChem - Wiley Online Library …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

Only four weeks to go until #DGHMVAAM2024 Annual Joint Conference in Würzburg🎉
Not registered yet ?!? ➡️t1p.de/nlfcw🏃‍♂️🏃‍♀️🏃

#dghm vaam2024 #VAAM #mikrobiologie #microbiology #microbes #viruses #dghm #hygiene #infektionsmedizin #infectionmedicine

Great work, to which we had the pleasure of contributing an absolute configuration by #VCDspectroscopy !

We are looking for a Bioimaging Facility Manager. If you have a passion for electron and/or light microscopy approaches and enjoy contributing to diverse research projects related to plant and microbial science, please apply! John Innes Centre.

We are hiring a postdoc in #directedevolution of multiple #enzymes in vivo in collaboration between DTU Biosustain Tailoring Proteins @ DTU Biosustain and the group of Donato García at Tec de Monterrey, Mexico. Deadline for applying is in 10 days (May 5th 2024). More info: nature.com/naturecareers/…

Something new in #biocatalysis : using an engineered flavoprotein oxidase, we could perform oxidative aminations! and more...
doi.org/10.1002/cctc.2…