Circulation Research #HIV and #CVD Review Series Alert!

' #Inflammation in HIV and its Impact on #Atherosclerotic Cardiovascular Disease' ahajrnls.org/3wPdfgq

Authored by Drs. Laventa Obare & colleagues.
Celestine Wanjalla

Circulation Research #HIV and #CVD Review Series Alert!

'HIV and Cardiovascular Disease' ahajrnls.org/450t5Bt
Authored by Drs. JM Afolabi & Annet Kirabo D.V.M., M.Sc., Ph.D., F.A.H.A.

Ma & colleagues found that lactate accumulation mediated by #NR4A3 promotes the progression of medial #arterial #calcification through histone #lactylation . Learn more about how to limit #vascular calcification at ahajrnls.org/4bvT1az

Circulation Research May 24th Issue is Out! ahajrnls.org/3wPOBJJ

Cover: Enhanced glycolysis mediated by #NR4A3 results in increased lactate thereby facilitating VSMC phenotype transition & ultimately contributing to the progression of arterial medial calcification.

Tikhomirov & colleagues found that blocking #GR signaling abrogated ion channel rhythms & subsequently morning #VA . Learn about a potential new chronotherapeutic strategy to suppress VA occurrence at ahajrnls.org/3yo7p62

Mendoza et al found the balance between Ca2+ & #ROS concentrations can dictate which #necrotic cell death pathway ( #mPTP vs. #ferroptosis ) becomes initiated at the level of the #mitochondria during #I /R injury ahajrnls.org/4dQjst6

Arielys Mendoza Karch Lab

Check out the latest review in the May 10th issue of Circulation Research by Roman-Campos & colleagues on ' #Arrhythmogenic Manifestations of #Chagas Disease: Perspectives from the Bench to Bedside' at ahajrnls.org/3UFvCMM

Check out the latest review in the May 10th issue of Circulation Research by Hennis & colleagues on 'Pacemaker Channels and the Chronotropic Response in Health and Disease' at ahajrnls.org/44KsYKl

Chen et al found that regulation of the integrity of protein structure by #endosomes & #lysosomes are important for controlling the #inflammation of the #heart and blood #vessels . Learn more at ahajrnls.org/3yi4cF6

JunxiongChen

Wang & colleagues found that the orphan G-protein coupled receptor (GPCR) #GPCRC5C regulates #AngII dependent #vascular #contraction . Learn more at ahajrnls.org/4dGDlTv

Tianpeng Wang @shamitkr

Zifkos & colleagues found that deleting #PTP1B in ECs ramps up #clot formation by boosting #VWF #exocytosis , shedding light on how blood clots in veins could be better understood and treated at ahajrnls.org/4byqkcG

Konstantinos Zifkos @tmuenzel Christophe Dubois Felix

Tamiato et al found that #RGS5 is a crucial regulator of pericyte function, & its deletion causes cardiac dysfunction & induces myocardial #fibrosis in a #TGFβ dependent mechanism. Learn more at ahajrnls.org/4ak0MPF

Anita Tamiato Guillermo Luxán Wesley Abplanalp

Check out the latest review in the May 10th issue of Circulation Research by Afolabi & colleagues about 'Salt-Sensitivity of Blood Pressure' at ahajrnls.org/3UhwQz7

Annet Kirabo D.V.M., M.Sc., Ph.D., F.A.H.A. Sepiso K Masenga, PhD Antentor Othrell Hinton, Jr PhD (A.J. Hinton)

Ramirez et al provides valuable insights into the resilience of developmental mechanisms, shedding light on the robustness & plasticity involved in the development of #PAA -derived #vasculature . Learn more at found at ahajrnls.org/3QDHzBk

Sophie Astrof 🇺🇸🇮🇱

Circulation Research May 10th Issue is Out! ahajrnls.org/3wPOBJJ

Cover: A 3D reconstruction of confocal slices from an E14.5 mature aortic arch with its branches that was depth-color-coded & overlayed on an image of the Delicate Arch in Arches National Park, Utah.