Great talk from #ESTRO37 health economic session. adrien paix shows how #sbrt is more cost effectiv compared to lobectomy in early stage #lungcancer .

So honoured to present our data d on targeting rep stress in one of the most dead-dealing sarcoma during #CTOS2023 . ATRi seems to be a promising agent alone and with irradiation. Thank you CTOS for highliting these ultrare Tumors in a special session. Centre Leon Berard

Analyse commentée rédigée par Waisse WAISSI, MD PhD sur l’article de Ohri N, et al. Pract Radiat Oncol 2021 Qui bénéficie le plus de l’immunothérapie adjuvante par #durvalumab après #radiochimiothérapie pour un cancer bronchique non à petites cellules ? bit.ly/3DwNvTJ

Analyse commentée : Waisse WAISSI, MD PhD sur l’art de BousabarahK, &al.RadiatOncol2021 Apport de la radiomique pour l’évaluation de la toxicité pulmonaire et de la réponse au traitement après radiothérapie stéréotaxique robotisée des cancers bronchiques localisés bit.ly/3m2rXYb

➡️ Up next at #ESMOSarcomaAndRareCancers24 : The session on unsolved questions in STS starts at 2:15 p.m. CET.
It features talks by:
⭐ Ingrid Desar of Radboudumc
⭐ Dario Callegaro of Istituto Tumori
⭐ Dr. Maud Toulmonde of Institut Bergonié
⭐ Waisse WAISSI, MD PhD of Centre Leon Berard, Genetics, Epigenetics and Biology of Sarcomas

Impact of histological subtype on radiological and pathological response after neoadjuvant radiotherapy in soft tissue #sarcoma

Benoît Allignet Waisse WAISSI, MD PhD European Society of Surgical Oncology (ESSO) TARPSWG Sarcoma European LatinAmerican Network (SELNET) Sarcoma Alliance @SoMe4sarcoma Oncology Advance RadOnc Tables

bit.ly/3uSZryd

Our systematic review with pooled analysis of preclinical data of #RTdrugcombo in #pancsm is online Critical Reviews in Oncology Hematology (CROH). #Radiosensitization depends on the type of DDRi and genomic background of cancer cells.
#radbio
sciencedirect.com/science/articl…

What a great day for #pancsm and #radonc at #asco18 . PREOPANC-1 : still a place for #radiotherapy in preoperative setting : Twice more R0 resection after irradiation vs upfront surgery. waiting for final analysis Next : neoadj mFOLFIRINOX --> #sbrt --> Surgery. x.com/asco/status/10…

'PROs are desired by patients, enable clinicians to efficiently address the whole patient, and make a difference in clinical outcomes.' We are in 2018 and tools exist. what are we waiting for ? #radonc #oncology Guihard MD x.com/asco/status/10…

Amazing work from Bastien Nguyen showing that 🧬chromosomal instability is ⬆️correlated with metastatic burden in many tumors type such as #pcsm #lcsm #bcsm . This could help to better define a 🔬biology-based #oligomet state. Huge implications for future #radonc ☢️trial.

Happy to share with you our recent #review assessing the role of #Radiotherapy for unresectable soft tissue #sarcoma . Another team work with Benoît Allignet.
Future studies in Centre Leon Berard w/ biomarkers, Modern #RT technique, hypofractionation and #RT drugcombo coming shortly.

Pattern of response of soft tissue #sarcoma after neoadjuvant radiotherapy. Great team work Centre Leon Berard & #radonc resident superstar Benoît Allignet
Still so much work to do to individualize treatment. Next steps : transcriptomic 🧬biomarkers of response, #RTdrugcombo . Stay tuned

Very proud to share our clinical data published by Radiotherapy & Oncology showing the benefit of definitive #RT for soft tissue #sarcoma using modern Radiation therapy techniques. Another great multidisciplinary management with Benoît Allignet Jean-Yves Blay Ray-Coquard Isabelle Centre Leon Berard

Possible cancer drug repurposing. Brain penetrant ATM Inhibitor AZD1390, promote Axon regeneration and functionnal recovery after spinal cord injury. Anthony Chalmers 💙
onlinelibrary.wiley.com/doi/10.1002/ct…

Proud of our former #radonc resident 👨‍⚕️ Benoît Allignet for this amazing work showing the pattern of response of #sarcoma after neoadjuvant radiotherapy ☢. Great team work Centre Leon Berard
Next step : transcrptomic 🧬biomarkers of response
ejso.com/article/S0748-…

Kudos 👏 to our former 🇧🇪fellow Dario Di Perri, MD, PhD for this amazing 🇫🇷french national study led by Centre Leon Berard

Recently Anthony Chalmers 💙 and colleagues show how PARPi could reduce radiation indiced neuroinflamation. DDRi have so much other effect that need to be assessed. academic.oup.com/noa/article/4/…

We all *hate* CIC-rearranged sarcomas
#CTOS2023 Waisse WAISSI, MD PhD shows these cells have very high replication stress, a potential therapeutic target!
#CTOSTweeTOS

We made an important update of the prostate cancer form survey in radiation therapy of MOSAIQ with Centre Leon Berard and Waisse WAISSI, MD PhD radiation therapy team. Something more simple and efficient. Thanks to Elekta we will spread it soon. We keep going.

Benoît Allignet The Oncologist Centre Leon Berard Waisse WAISSI, MD PhD Ray-Coquard Isabelle Jean-Yves Blay Great job Benoît Allignet