This is definitely one of the longest running projects in the lab b/c we were stuck in a trap of thinking about Sie proteins blocking competing phages. But wasn't a satisfying answer to fit the biology we observed - kudos to Véronique Taylor for persevering and figuring it out!

New prepint alert @themaxwelllab! 📢 📢 📢 Superinfection exclusion (Sie) proteins aren’t just for defence – they also ensure the spread of viral progeny! Prophages that lack Sie proteins devour their young via a process we call the Kronos effect.
biorxiv.org/content/10.110…

I am thrilled to share our work on a novel prophage-encoded phage defence from Karen Maxwell:

Anti-phage defence through inhibition of virion assembly
nature.com/articles/s4146…

This old dude band’s cover of Tiffany’s “I think we’re alone now” made.my.year.

Out today in Mol Micro Editors:

Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in P aeruginosa
doi.org/10.1111/mmi.15…

With our 🇨🇦 friends Eric Déziel and Karen Maxwell

Day 1 of the AMR Symposium kicks off, with over 200 online and in-person participants. For more information about today's conferences, click here: biomerieux.ca/en/amr-symposi… #bioMérieux #EPIC #OHC #AMMI #AMR

Congratulations to Gary Bader, Benjamin Blencowe, Timothy Hughes and Mikko Taipale on their chair appointments! 👏

The appointments will support research in disease biomarkers, gene regulation and host-pathogen interactions. #UofT

Learn more 👉 uoft.me/ChairAppointme…

.bioMérieux Canada partners with AMR - One Health Consortium for its second Antimicrobial Resistance Symposium, November 22 and 23!
Virtual or in person, register here: reg.eventmobi.com/AMR2023
#AMR #bioMérieux

Less than a month away from the second annual symposium on #AMR !

We're so excited to partner with bioMérieux Canada again this year to bring you an exciting two-day program on the latest advances to tackle AMR.

Register now to reserve your spot!

.bioMérieux Canada partners with U of T Emerging and Pandemic Infections Consortium for its second Antimicrobial Resistance Symposium, on November 22 and 23! Virtual or in person, register here: reg.eventmobi.com/AMR2023 #RAM #WaaW #bioMérieux #EPIC

Join the crew and apply for a fully-funded PhD position in our lab John Innes Centre to study how multicellular bacteria control their cell cycle in response to DNA damage. For more information and how to apply 👉shorturl.at/ELN47.

📢 Meet Canadian experts in antimicrobial resistance on November 22 & 23, at the 2nd Symposium organized in partnership with U of T Emerging and Pandemic Infections Consortium, AMMI Canada and AMR - One Health Consortium. To attend virtually or in person, register here: reg.eventmobi.com/AMR2023 #RAM #WaaW

Véronique Taylor on prophages listen-in on bacterial communication to activate anti-phage defence! Véronique Taylor Karen Maxwell

PIT2 #protein blocks #Pseudomonas QS system by LasR interaction, inhibiting T2SS #virulence (LasA & PrpL). Foundation for a #phage -inspired anti-virulence #therapy ?
Check our #research in iScience journal
bit.ly/Schroven_iScie…

#microbiology #biotechnology #BIONICBACTERIA #synbio

We are looking for the next editor to lead the microbiology & immunology section of PLOS Biology

Do you have micro/immuno expertise (inc virology ofc) & a passion for science away from the bench? Get in touch w/ any Qs!
Assoc or Senior
Applications assessed upon receipt
Pls RT

Care to chime in here aled edwards? I know you have some good ones! 😂

The University of Toronto, Department of Biochemistry is searching for an Assistant Professor, Teaching Stream. FYI, these positions are analogous to research 'tenure-stream' in that following a successful 6 yr review promotion is to Associate Prof (continuing status).

Three of the more costly and frequently used reagents in molecular biology are rolling circle amplification (RCA) mix, chemically competent MachOne (or other E. coli) cells, and Gibson assembly mix. Postdoc Julian Willis—who is starting his own lab in the UK soon—developed

Did you enjoy @crispr2023 or want to come to the next one! The #crispr conference will be in ⁦ChristchurchNZ⁩ organised by ⁦Peter Fineran⁩, ⁦Dipa Sashital⁩ ⁦Gavin Knott⁩ and ⁦Bridget Watson⁩. Check out the website crispr2025.org

Phage tRNAs evade tRNA-targeting host defenses through anticodon loop mutations
elifesciences.org/articles/85183
Really nice work Daan F van den Berg!