Seminoma
• #1 testicular germ cell tumor
• Syncytiotrophoblastic cells may be seen
• Associated testicular atrophy can be seen 👇
• IHC:
OCT3/4; KIT/CD117; SALL4 +
CD30 and AFP -
#pathagonia #pathx #gupath #pathology #seminoma #pathology #medx
🔬 #COTW by Meredith Herman, DO!
A 62-year-old female with dx of breast cancer who presents with lymphedema and new breast lesion.
What top 2 stains would you order to confirm the diagnosis? What is the diagnosis?
#PathX #UMichPath #BreastPath
Image of the Week!
Submitted by: Mariia Ivanova, M.D., Ph.D.
Directory Profile: buff.ly/3KoAq4g
Subspecialty: Medical renal
Diagnosis: GATA3 normal expression in fetal kidney
#PathTwitter #PathX #PathologyOutlines #Image #Kidney
Gastric Xanthoma
• Benign
• Endoscopically 👀 as yellow-white nodules
• Most common location-Antrum
• Foamy macrophages in lamina propria
• Etiology unclear
• Associated with background gastric pathology
#pathagonia #path4people #gi path #pathx #gi #gastroenterology
S100
• Stains Schwann cells and melanocytes
• Stains Adipocytes
• Stains (I often forget) myoepithelial cells in breast too 👇
#pathagonia #path4people #pathx #ihc #s100 #pathtwitter #breastpath
A nice example of Paget disease of the breast. The second picture is the underlying DCIS. #pathology #breastpath #pathresidents #pathtwitter #pathx
🎉We are exited to announce a series of 2 free webinars with the subject 'Digital transformation of the pathology laboratory'!
Part 1 is scheduled for 4 June at 14:00 CEST!
Programme and registrations 👇👇👇
smartzoom.blob.core.windows.net/upload/sites/1…
#PathTwitter #PathX
#DigiPath
#pathology
Spironolactone Bodies
• Concentric lamellations 👇
• Seen in adrenal tissue of pts with primary hyperaldosteronism (Conn syndrome) treated with aldosterone anatogonists (eg. Spironolactone)
• Adrenalectomy done as medications were ineffective
#pathagonia #pathx #pathtwitter
Today’s #eyeSCANdy shows a scanning EM of a normal papillary tip showing ostia of the ducts of Bellini.
Photo courtesy of Dr. Stephen Bonsib. #PathTwitter #PathX #RenalPath
#breastpath #lymphnode
Breast biopsy in young woman.
Radiology saw amorphous calcifications. 🩻
You, the pathologist, see this.
❓What do you do next?
#pathpuzzle #PathX #radiologist
🔬 Unexpected guest in today's bronchoalveolar lavage smear slide! 🐾 Sometimes you find the most surprising patterns in pathology! #Pathology #pathart #pathx #cytology #cytopathology #Cyto #Cyto path #Pathologists Cytopathology.org Syed Z. Ali
#Breastpath
🧵Challenging differential diagnosis
Columnar cell changes and micropapillary ADH
Dr Sciallis Cleveland Clinic MPS #EverydayBreast #pathtwitter #PathX #pathology #PathResident #NIPPathX
#EverydayBreast
Nodular PASH (pseudoangiomatous stromal hyperplasia)
-They can look like a fibroadenoma
-🔬high power: cracked pseudovascular spaces
- CD34 ➕and show some ER positivity
Dr Sciallis CCMSS #Breastpath #pathtwitter #PathX #pathology #PathResident #NIPPathX
Exciting news! Dr. Neil Theise's book, 'Notes on Complexity: A Scientific Theory of Connection, Consciousness, and Being,' has won the NAUTILUS BOOK AWARDS Award Gold Medal in Science and Cosmology! Congratulations on this big achievement! #Pathtwitter #PathX