Ashkan Shoamanesh(@Ash_Shoamanesh) 's Twitter Profile Photo

Important results from an IPDMA of the PACIFIC program (AF, AMI and stroke). Asundexian has⬇️rates of bleeding🩸compared with apixaban. Compared with placebo, asundexian 50 mg has similar rates of major + all bleeding, but with⬆️risk of CRNM bleeding.
sciencedirect.com/science/articl…

Important results from an IPDMA of the PACIFIC program (AF, AMI and stroke). Asundexian has⬇️rates of bleeding🩸compared with apixaban. Compared with placebo, asundexian 50 mg has similar rates of major + all bleeding, but with⬆️risk of CRNM bleeding. 
sciencedirect.com/science/articl…
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Bas Uijterwijk(@Bas_Uijterwijk) 's Twitter Profile Photo

📈Rising MIPD adoption, but PD indications are diverse
Our IPDMA pioneered in NPPC subgroup stratification
Short-term MIPD safety ✅ for all NPPCs
🏁Limited long-term data reveal research gap in MIPD safety for AAC, dCCA, and DAC Mohamed Abu Hilal
Thnks to all participating centers🙏🏼

📈Rising MIPD adoption, but PD indications are diverse
Our IPDMA pioneered in NPPC subgroup stratification
Short-term MIPD safety ✅ for all NPPCs
🏁Limited long-term data reveal research gap in MIPD safety for AAC, dCCA, and DAC @Abuhilal9Abu
Thnks to all participating centers🙏🏼
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Joshua Kock(@Jkock21) 's Twitter Profile Photo

You're planning an IPD meta-analysis, but, is it worth it? Great talk at by Richard Riley (R²).
You should plan to calculate your power of the IPDMA and plan accordingly.

You're planning an IPD meta-analysis, but, is it worth it?  Great talk at #CochraneLondon by @Richard_D_Riley. 
You should plan to calculate your power of the IPDMA and plan accordingly.
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Thomas Meinel(@TotoMynell) 's Twitter Profile Photo

Nice tweetorial on large core LVO. At , MAGNA collaboration results of large core RCT IPDMA led by Amrou Sarraj were presented. Basically benefit of all subgroups, only exception core >150ml (although favourable trend).

Nice tweetorial on large core LVO. At #ESOC23, MAGNA collaboration results of large core RCT IPDMA led by @amrsarrajMD were presented. Basically benefit of all subgroups, only exception core >150ml (although favourable trend). 
#GTFVO
#NoLVOleftbehind
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Vinson Chan(@VinsonChan) 's Twitter Profile Photo

Huge success The Society of Radiologists in Training annual conference this week!
Congrats elisa lau and ELIXIR group for special commendation for IR poster!
Best urorad poster for our VISION IPDMA! UCL Div of Surgery PRIME Trial UCL
Best oral presentation on our renal tumour biopsy work! Professor Tze Min Wah UniLeedsMed&Health 💙

Huge success @_the_SRT annual conference this week!
Congrats @elisalausw and ELIXIR group for special commendation for IR poster!
Best urorad poster for our VISION IPDMA! @UCLDivofSurgery @PrimeMRI
Best oral presentation on our renal tumour biopsy work! @TzeWah1 @LeedsMedHealth
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Behnood Bikdeli(@bbikdeli) 's Twitter Profile Photo

Can we do better for pt stratification for PE diagnosis? Large collaborative IPDMA, robust protocol & stats, also w interaction term for d-diner w age, limited w lack of some covariates. Excellent discrimination, fig c/w other models Erik Klok North American Thrombosis Forum ISTH

Can we do better for pt stratification for PE diagnosis? Large collaborative IPDMA, robust protocol & stats, also w interaction term for d-diner w age, limited w lack of some covariates. Excellent discrimination, fig c/w other models @Erik_Klok_MD @NATFthrombosis @isth #ISTH2023
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Alain Amstutz🇨🇭🇱🇸(@AlAinAmstutz) 's Twitter Profile Photo

Collected and analyzed individual patient data from all major trials, incl. World Health Organization (WHO) , , among others. This covers over 10,000 hospitalized patients from more than 40 countries. thelancet.com/journals/lanre…

Collected and analyzed individual patient data from all major #remdesivir trials, incl. @WHO #SOLIDARITYtrial, #ACTT1, #DISCOVERYtrial among others. This #ipdma covers over 10,000 hospitalized #COVID19 patients from more than 40 countries. thelancet.com/journals/lanre…
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Jean-Jacques Parienti(@JjParienti) 's Twitter Profile Photo


4 or 5/7 days 3DR met 4% non-inferiority margin compared to 7/7 days

No VF at W48 in B/F/TAF or DTG-based intermittent 3DR

All VF had large HIV-DNA reservoir at baseline

#EACS2023 
4 or 5/7 days 3DR met 4% non-inferiority margin compared to 7/7 days

No VF at W48 in B/F/TAF or DTG-based intermittent 3DR

All VF had large HIV-DNA reservoir at baseline

#IPDMA
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Elissa Campbell(@Elissa_Campbell) 's Twitter Profile Photo

How else to tailor treatment? Individual Participant Data Meta analysis (IPDMA). In contrast to traditional meta analysis in geriatric medicine, which doesn’t look at subgroups of older people to allow for targeting interventions most efficiently Andrew Clegg

How else to tailor treatment? Individual Participant Data Meta analysis (IPDMA). In contrast to traditional meta analysis in geriatric medicine, which doesn’t look at subgroups of older people to allow for targeting interventions most efficiently @drandyclegg #anzsgm2024
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Josefien Breedvelt, PhD(@JosefienUMH) 's Twitter Profile Photo

Excited to be at in Washington DC. The programme looks brilliant.

I’m looking forward to present on IPDMA, ML and large scale AI-meta-analyses (at below symposia).

If you’re around let me know, I’d be great to meet. 👋🏻

Excited to be at #APS2023 in Washington DC. The programme looks brilliant.

I’m looking forward to present on IPDMA, ML and large scale AI-meta-analyses (at below symposia).

If you’re around let me know, I’d be great to meet. 👋🏻
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Stephanie Haering(@sthaering) 's Twitter Profile Photo

Anke de Haan took us on a journey of how to conduct an an individual participant data meta-analysis (IPDMA), sharing insights on the chances and pitfalls along the way. Such cool work! (And so much work!) Thank you, Anke, for this hands-on presentation! 5/x

Anke de Haan took us on a journey of how to conduct an an individual participant data meta-analysis (IPDMA), sharing insights on the chances and pitfalls along the way. Such cool work! (And so much work!) Thank you, Anke, for this hands-on presentation! #DeGPT 5/x
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Richard Riley (R²)(@Richard_D_Riley) 's Twitter Profile Photo

Better late than never 😀

Finally met in-person with Lesley Stewart & Jayne Tierney, 3 years after our IPD meta-analysis book was published!

We began in 2014, so a long journey, but rewarding to see the book (& ipdma.co.uk) now helping others on their IPDMA projects 🙏

Better late than never 😀

Finally met in-person with @LesleyCRD & Jayne Tierney, 3 years after our IPD meta-analysis book was published!

We began in 2014, so a long journey, but rewarding to see the book (& ipdma.co.uk) now helping others on their IPDMA projects 🙏
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Kari Tikkinen(@KariTikkinen) 's Twitter Profile Photo

8⃣ Individual patient level data meta-analysis (IPDMA) uses data at the participant level to synthesize evidence on clinical decision-making and provides a unique opportunity to study effect modifiers at the participant level

eu-focus.europeanurology.com/article/S2405-…



10/14

8⃣ Individual patient level data meta-analysis (IPDMA) uses data at the participant level to synthesize evidence on clinical decision-making and provides a unique opportunity to study effect modifiers at the participant level

eu-focus.europeanurology.com/article/S2405-…

#EBM

10/14
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Rosa for QSP(@RosaQSP) 's Twitter Profile Photo

Tutorial: Pharmacokinetic analysis across studies to drive knowledge‐integration: A tutorial on individual patient data meta‐analysis (IPDMA) buff.ly/3JdHiRQ

Tutorial: Pharmacokinetic analysis across studies to drive knowledge‐integration: A tutorial on individual patient data meta‐analysis (IPDMA) buff.ly/3JdHiRQ
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Wong yujun(@wong_yujun) 's Twitter Profile Photo

Non-invasive test (NIT) to prognosticate :

✅Fibrosis staging – moderate performance (vs biopsy)
✅LRE – FIB-4 / LSM comparable to biopsy
- IPDMA from LITMUS_Project
Read👉tinyurl.com/yckbmsnu

@EASLCongress Hannes Hagström EASL Education

Non-invasive test (NIT) to prognosticate #NAFLD:

✅Fibrosis staging – moderate performance (vs biopsy)
✅LRE – FIB-4 / LSM comparable to biopsy
- IPDMA from @LITMUS_IMI 
Read👉tinyurl.com/yckbmsnu

@EASLCongress @HannesHagstrom @EASLedu
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PsychiatryAmsterdam(@PsychRes) 's Twitter Profile Photo

New out showing that higher symptom severity was linked to larger symptom reductions after in patients with social disorder. The findings suggest that clinicians can confidently offer CBT to individuals with severe SAD symptoms. buff.ly/3JHo8UO

New #IPDMA out showing that higher symptom severity was linked to larger symptom reductions after #CBT in patients with social #anxiety disorder. The findings suggest that clinicians can confidently offer CBT to individuals with severe SAD symptoms. buff.ly/3JHo8UO
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CCCF(@CCCForum) 's Twitter Profile Photo

Fernando Zampieri follows with his IPDMA on fluid choice in critical care. Balanced solns likely to be beneficial for the majority of critically ill pts (IH mort, absolute benefit likely small) but importantly, very likely to be harmful for TBI pts

@f_g_zampieri follows with his IPDMA on fluid choice in critical care. Balanced solns likely to be beneficial for the majority of critically ill pts (IH mort, absolute benefit likely small) but importantly, very likely to be harmful for TBI pts
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Grant H Brenner MD(@GrantHBrennerMD) 's Twitter Profile Photo

Review of EMDR's effectiveness for PTSD

C/w with other reviews it's about as effective as other therapies.

Have yet to see any scientific data to support that anything other than exposure and regular therapeutic processes are what works here.

Results
One-stage IPDMA found no

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Todd Rice(@toddrice_ICU) 's Twitter Profile Photo

More data favoring balanced crystalloids over saline in critically ill patients. BEST-Living IPDMA published in Lancet Resp Med. The one excepted population that we know is traumatic brain injury - saline better in pts with TBI. thelancet.com/journals/lanre…

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