HEPATOCELLULAR

VS

CHOLESTATIC

Good morning Family. Let’s help support Shiraz’s fight against Hepatocellular Carcinoma. Every contribution counts. God bless you as you do.

Kindly Like and Rt for a wider reach

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update

ascopubs.org/doi/10.1200/JC…

Our liver transplant surgeon Dr. Ashton A Connor will speak at #ILTS2024 on how prospective molecular profiling of hepatocellular carcinoma can inform precision transplant oncology strategies. spr.ly/6011jHb99

'Analysis of the Upregulated Expression Mechanism of Apoptotic Chromatin Condensation Inducer 1 in Hepatocellular Carcinoma Based on Bioinformatics' sheds light on the regulatory mechanisms of Acin1 in HCC, highlighting the potential role of miR-674-5p as a key regulator. 🔬

Good day all. Our friend and brother Rashid Shiraz is fighting against Hepatocellular Carcinoma but will needs our support to win.

Let’s kindly contribute any amount we can to support.

Thank you.

The Janus Face of Serotonin

This study presents an overview of the existing literature, focusing on the role of #serotonin (5-HT) in hepatocellular carcinoma, cirrhosis, fatty liver disease, viral hepatitis, and #liver injury.
sciencedirect.com/science/articl…
J P Fanton

A 2023 systematic review found 49 papers reported instances of liver tumors in the setting of testosterone administration or endogenous overproduction, including hepatocellular adenoma, hepatocellular carcinoma, cholangiocarcinoma, or other biliary neoplasm.

PSC-IBD is a/w higher risk of certain cancers:
- cholangioCa
- gallbladder Ca
- colorectal Ca
- hepatocellular Ca (if cirrhotic)
- ?pancreatic Ca

Screening with:
- US (+/- MRC, CA 19-9) every 6 -12 mths
- annual colonoscopy (high-def, random biopsies)

🩸Indolent T lymphoblastic proliferation (IT-LBP) is an extra-thymic non-clonal expansion of T-lymphoblasts

🩸It occurrs alone or in association with other disorders, including Castleman disease (as illustrated in below Figures 1-3) and others (myasthenia gravis, hepatocellular…

Adjuvant and neoadjuvant immunotherapies in hepatocellular carcinoma

A great review for weekend reading👇

nature.com/articles/s4157…

Highlights of Day 1 ' Hepatocellular carcinoma Conference '

Presenting our study at GI-ASCO: Agrin as a potential biomarker in Hepatocellular Carcinoma. Thanks to mentors, Dr. Iyer and Dr. Chakraborty Renuka Iyer Riya Patel, MD Roswell Park Hematology/Oncology Fellowship

Highlights 🙌🏻of the phase II RENOBATE trial on Regorafenib + Nivolumab in Unresectable Hepatocellular Carcinoma (uHCC) evaluating the efficacy of the Regorafenib-Nivolumab combination as first-line treatment for uHCC.
👥A total of 42 patients received 480 mg of nivolumab every 4…

Even thinking about the importance of diagnostic guidelines in managing HCC?

Welcome to this #tweetorial based on “Comparison of Four Diagnostic Guidelines for Hepatocellular Carcinoma Using Gadoxetic Acid–enhanced Liver MRI” published in Radiology

An interesting article😱👉 on the current status, advances and challenges in pharmacotherapy for hepatocellular carcinoma (HCC), preeminent among liver neoplasms, carries a significant burden of morbidity and mortality at a global level. Although its classic etiology is linked to…

Graphical abstract 9/16/23
#abdradj #radiology

Understanding the role of radiologists in complex treatment decisions for patients with hepatocellular carcinoma.

Omar Kamal Bob Marks, MD, FSAR Jimmy Lee Ania Kielar Khaled Elsayes Alice Fung, MD

shorturl.at/entwR

📊 Just published this month! Original Article: 'Prognostic Value of S100 Family mRNA Expression in Hepatocellular Carcinoma' explores the prognostic significance of S100 family members in HCC, shedding light on their potential roles in disease progression. 🧬

Insulin resistance is implicated in both the pathogenesis of #MASLD and its progression from steatosis to steatohepatitis, cirrhosis, and even hepatocellular carcinoma. ADA Professional Publications American Diabetes Association
diabetesjournals.org/spectrum/artic…

1/5
📣New study shows that HCC screening is associated with reduced mortality.

Importantly, lead-time and length-time biases were accounted for🙌

Want to know more about these biases? 🧵👇

#livertwitter JAMA Network Open BCLC Darine Daher Amit G Singal
jamanetwork.com/journals/jaman…