Anabolic androgenic steroids (AAS) use among cisgender gay, bisexual, and queer men was found to be associated with multifactorial motivators, including a likely AAS use disorder and muscle dysmorphia. Eric Kutscher MD ja.ma/3UJhUZr

In this prospective diagnostic study, a composite eye-tracking biomarker was predictive of best-estimate diagnosis of autism, and an integrated diagnostic model including PCP diagnosis and diagnostic certainty showed improved sensitivity and specificity. ja.ma/3K16Ce4

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Is the long-term consumption of olive oil associated with dementia-related death risk?

ja.ma/3wuYr6r

Results of this secondary analysis suggest that chlorthalidone may be associated with reduced major adverse CV events and noncancer deaths in patients with prior MI or stroke compared with hydrochlorothiazide. ja.ma/3UExhCo

In a survey of PCPs and GI-Hep providers across 5 US safety-net health systems, knowledge gaps and perceived barriers to HCC surveillance were identified, which can targeted with educational interventions to improve HCC surveillance in cirrhosis patients. ja.ma/3UF3kSw

US survey shows high public approval for biotechnology that allows prospective parents to select embryos based on their DNA. With commercial availability but lack of regulation, informed dialogue is crucial for bridging public and healthcare perspectives. ja.ma/3ygiHtg

Study found 7 cord blood proteins associated w/ birth weight & growth trajectories early in life. This suggests stressors that could affect the cord blood proteome during pregnancy might have long-lasting associations w/ weight & body anthropometrics. ja.ma/4bilUXR

A meta-analysis of longitudinal studies of coronary disease in HIV found that people with HIV have a higher risk of all-cause mortality, recurrent event and admission for heart failure following acute coronary syndrome or revascularization. ja.ma/3QL9Gyq

In sub-Saharan Africa the 5-year breast cancer survival rate is estimated to be 40% in this study, highlighting the urgent need for improved health care resources and strategies. ja.ma/4dyJ51H

Half of Medicare-approved physicians also participate in the Veterans Health community care network. Participants are more likely to practice in rural or healthcare professional shortage areas and have higher MIPS quality scores than non-participants. ja.ma/44DV2z0

Research by American Institutes for Research finds that for Medicare beneficiaries, areas with the highest telehealth usage through 2021 had higher rates of clinician encounters, total cost of care, and hospitalizations compared to areas with the lowest telehealth uptake. ja.ma/44JIwhh

For patients who were hospitalized with acute kidney injury (AKI), this study found time-dependent mediations on the associations of BP with mortality and readmission, which may inform the ideal degree and timing of post-AKI blood pressure treatment. ja.ma/3QIfusx

This study finds that pregnant patients with congenital heart disease (CHD) have higher total ($8300) and out-of-pocket ($700) costs, linked more to pregnancy-related medical conditions and birth outcomes, as opposed to CHD anatomic severity. ja.ma/44HNRWg

This cohort study reported the largest newborn screening for 6 lysosomal storage disorders (LSDs) using the tandem mass spectrometry in China. The combined birth prevalence of the 6 LSDs was 1 in 1856 births. ja.ma/3UVtxO8

In this study of Asian American, Native Hawaiian, and Pacific Islander children and adolescents, the median age at pubertal onset varied substantially across ethnic subgroups, even among youths with healthy weight. ja.ma/3WCZvji

RCT: Acupuncture may be effective to treat symptoms of dry mouth and improve and overall quality of life for patients with head and neck cancer with radiation-induced xerostomia ja.ma/3yfvYCn

Most viewed in the last 7 days from JAMA Network Open:

Is the long-term consumption of olive oil associated with dementia-related death risk?

ja.ma/4bzKmno

This study finds that the accuracy and prognostic performance of the simplified Geneva score and other validated risk models to predict VTE is limited (AUC<60%) and their clinical usefulness may be questionable. ja.ma/3JW8uVb

A variety of structural disadvantages are illustrated in this cross-sectional study of county-level sociodemographic and geographic characteristics associated with the prevalence of Black physicians in the earliest days of the profession. ja.ma/4bB56ep

Meta-analysis: 20% of US adults who die by suicide spent at least 1 night in jail in the year prior to death. This high-risk group needs community suicide screening and prevention services. ja.ma/4bdZSoU