🇮🇳🇬🇧-🇪🇺🇳🇱
👉The first genetically confirmed cohort of #FSHD from Northern India
💡Evidence of differences relevant to clinical diagnostics and underscores the need for global FSHD participation in research and trial-ready Indian FSHD cohorts.
📰pubmed.ncbi.nlm.nih.gov/38664571/
vishnu v y

🇺🇸🇨🇦 - 🇪🇺🇪🇸🇫🇷🇳🇱🇸🇪

👉Safety and efficacy of #losmapimod in #FSHD : a randomised, double-blind, placebo-controlled phase 2b trial

💡Although it did not change DUX4-driven gene expression. Potential improvements in muscle & patient-reported global impression of change

🇪🇸 FSHD España community

🇬🇧 #FSHD community

It is always sweet to hear these words, but let us continue until we are healed.
FSHD Society FulcrumTx SOLVE FSHD LivingwithFSHD

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👉Optimization of Xenografting Methods for Generating Human Skeletal #Muscle in Mice.

👉Methods to generate mature muscles in immunocompromised mice starting hMPCs from individuals #FSHD

📰pubmed.ncbi.nlm.nih.gov/38600801/

Project Mercury Sharif Tabebordbar Emanuele Mocciaro

🇺🇸 -🇪🇺🇳🇱
👉Regional & bilateral #MRI & gene signatures in #FSHD : implications for clinical trial design & disease progression

💡Systemic immune cell infiltration of skeletal muscle might have a role in disease progression

pubmed.ncbi.nlm.nih.gov/38268317/
Mark Christman Stanford Neurology & Neurological Sciences

🇯🇵
👉 #FSHD Health Index: Japanese translation and validation study

💡The FSHD-HI-J is a valid and reliable patient-reported outcome measure for Japanese patients

📰pubmed.ncbi.nlm.nih.gov/38555736/
FSHD Japan さとて@筋ジス（FSHD） Helen Walker iayaichi mocomoco ひよこ(車椅子) JWMDRC

Treatment with an antioxidant supplement led to improvements in muscle strength and life quality for FSHD patients in a small clinical trial. musculardystrophynews.com/news/antioxida…

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👉Muscle strength, quantity/quality & muscle fat quantity and their association with oxidative stress in patients with #FSHD : Effect of antioxidant supplementation

💡It might reduce ROS , promoting muscle function

📰sciencedirect.com/science/articl…

🇪🇺 🇳🇱
👉The complementary use of muscle ultrasound and MRI in #FSHD : Early versus later disease stage follow-up

💡 Muscle MRI appears better-suited to detecting & monitoring in later stages
📰pubmed.ncbi.nlm.nih.gov/38521678/
#dux4 #Biomarker #MRI #muscle
Nicol Voermans FSHD nieuws

🇪🇺🇧🇪 -🇬🇧
👉The DUX4-HIF1α Axis in Murine and Human Muscle Cells: A Link More Complex Than Expected

💡HIF1α in DUX4 toxicity is complex
pubmed.ncbi.nlm.nih.gov/38542301/
#fshd #dux4 #murine #muscle

Great date

Good news #fshd

#fshd research !!!

We are excited to announce promising preliminary data showing SAT-3247 can improve skeletal muscle function in a mouse model of facioscapulohumeral #musculardystrophy . We plan to present the data at the 2024 #MDAconference .

ir.satellos.com/news/news-deta…

#FSHD $MSCL $MSCLF

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👉
@Arrowheadpharma
announced that it has filed an application for clearance to initiate a Phase 1/2 clinical trial of ARO-DUX4, RNAi therapeutic being developed as a potential treatment for patients with #FSHD

businesswire.com/news/home/2023…
LivingwithFSHD

UILDM Dir. Naz.

🇰🇷
👉Prevalence of Neuromuscular Diseases in Young South Korean Males; A Korean Military Manpower Administration Data-Base

💡 #FSHD prevalence among the enlisted soldiers of 3.11 per 100,000

pubmed.ncbi.nlm.nih.gov/37455505/
Pilar Camaño Helen Walker
Alex L. 이정근 (He/Him)
FSHD Leiden

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🧬Avidity Biosciences, Inc. : AOCs provide promise as a new class of oligonucleotide therapeutics for the treatment of #FSHD

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SOLVE FSHD announces new collaborative research grants to accelerate novel potential therapeutics for #FSHD

👏👉 globenewswire.com/news-release/2…

FSHD Canada LivingwithFSHD Dystrophie musculaire Canada Muscular Dystrophy UK