'Le Désespéré'

Does not look like one to me...What is he really thinking about?

(Gustave Courbet, 1843–1845)

I just got the best phone call from my PhD graduate:
'I got the job'.

This is a tough market right now, at least in Pharma. So good luck to those looking for a job.

I'm looking to hire someone to help get the lab setup and experiments going (and potentially for longer) when I start my lab at the University of Minnesota this September. Please share and apply if interested! Link to the ad hr.myu.umn.edu/jobs/ext/361453

Check out our new structure of a histone H3T3 kinase that binds in a DNA supergroove - where the major grooves of adjacent DNA gyres face one another. No contacts with the histone octamer core - not even the acidic patch!

This 👇👇What an amazing memory for this graduating class (and frankly all of us!) #ImagineJHU JHU U'Grad Research

Stevie Wonder is commencement speaker at Hopkins

In a study funded by #CCBIR , Denis Wirtz Johns Hopkins Medicine et al. developed a #DeepLearning approach to improve 3D tissue mapping bioRxiv biorxiv.org/content/10.110….

Vince the Prince on his way to the Bayern?

Archie Gould (no relation) playing Bach for his co-workers

Great talk today by Lucie Dequiedt at #DDW2024 on her work in early detection for individuals at high risk of development of pancreatic cancer!

I am a very lucky PI.

Johns Hopkins Engineering Johns Hopkins University

Gang of five

Four amazing students from the group are graduating today with a PhD in chemical and biomolecular engineering ⁦⁦Johns Hopkins Engineering⁩

Johns Hopkins University⁩

Excited to share our latest paper! We show that current classifications of pancreatic lesions PanINs and IPMNs, which rely on 2D histologic size criteria, can fail when viewed in 3D. How else will 3D affect clinical practice?

Three bioRxiv releases from my lab last week, and one more today! From postdoc Markus Sommer, his new eukaryotic gene recognizer, PSAURON (the 'p' is silent), a successor to his bacterial gene finder Balrog #LOTR biorxiv.org/content/10.110…

CODA for the win!

nature.com/articles/s4159…
nature.com/articles/s4158…

Graduation day at ⁦Johns Hopkins University⁩

Four of my PhD students will be hooded later today

What makes an IPMN an IPMN? It's complicated! See our new collaborative work led by Ashley Kiemen that suggests new definitions are needed based on 3D analysis.

Another paper out today in the American Journal of Surgical Pathology! Recently, we’ve shown that PanIN are more abundant and genetically diverse than previously thought. Here, we expand on this to show that 3D imaging challenges the 2D classification criteria of PanINs.

Happy 229th birthday, Johnny Hop!