Stem Cells Translational Medicine is excited to announce Dr. Kim as the winner of its 2023 Young Investigator Award, recognising his paper as one of global significance.

Read the winner's interview and learn more about his research here: oxford.ly/49wR5xJ

Study evaluating the long-term safety and effectiveness of allogeneic-derived mesenchymal stem/stromal cell injections in the major salivary glands for the treatment of radiation-induced xerostomia: doi.org/10.1093/stcltm…

This study examined whether direct delivery of MSCs to the pancreas via intra-arterial injection would improve therapeutic efficacy. #diabetes doi.org/10.1093/stcltm…

This article reports on the application of a modified autologous cultured epithelial grafting technique developed for treating refractory vitiligo, with clinical outcomes that are encouraging for future therapies. doi.org/10.1093/stcltm…

This study provides some new insights into the molecular mechanism underlying age-related adipose stem cell (ASC) dysfunction, highlighting DUXAP10 and miR-214-3p as potential rejuvenating factors for aged stem cells. doi.org/10.1093/stcltm…

Read the March 2024 issue of Stem Cells Translational Medicine, now online Oxford Journals: academic.oup.com/stcltm/issue/1…
#openaccess #stemcells

This study aimed at establishing procedure that could improve stem cell therapy as a treatment for #Hirschsprung disease, a neuro-intestinal disease caused by migratory failure of enteric neural crest-derived cells during embryonic development. doi.org/10.1093/stcltm…

Results of this study indicate that #MSCs -Exo, but not #MRC -5 cell-derived (MRC-5-Exo) exosomes, have anti-inflammatory properties like their parental cells and therapeutic effects against acute lung injury in a dose-dependent fashion. #pyroptosis doi.org/10.1093/stcltm…

This article reports a dose-dependent evaluation of umbilical cord-derived MSC (Cellistem) in an experimental model and a dose-escalation phase I clinical trial of intra-articular injection for patients with knee osteoarthritis. doi.org/10.1093/stcltm…

Read the February 2024 issue of Stem Cells Translational Medicine, now online Oxford Journals: academic.oup.com/stcltm/issue/1…
#openaccess #stemcells

Transplantation of spinal cord progenitor cells (SCPCs) has beneficial effects on treating spinal cord injury. This study focused on transplantation #SCPCs derived from human iPSCs and the development of methods ensuring their safety. doi.org/10.1093/stcltm…

Stroke is a leading cause of death and disability, with limited treatment options. This study evaluated whether intravenous infusion of banked, non-HLA matched unrelated donor umbilical cord blood improved functional outcome after #stroke . doi.org/10.1093/stcltm…

Perspective:

Clinical Application of Umbilical Cord Mesenchymal Stem Cells Preserves β-cells in Type 1 Diabetes

Ashraf Al Madhoun, Lubaina Koti, Neus Carrió, Maher Atari, and Fahd Al-Mulla
doi.org/10.1093/stcltm…

Read the January 2024 issue of Stem Cells Translational Medicine, now online Oxford Journals: academic.oup.com/stcltm/issue/1…
#openaccess #stemcells

Thank you to all who contributed to the 12th volume of Stem Cells Translational Medicine. bit.ly/48wW80n

The December issue of Stem Cells Translational Medicine is now available online Oxford Journals: academic.oup.com/stcltm/issue/1…
#openaccess #stemcells

Study results show that cardiopoietic cell therapy has the potential to improve the quantity and quality-of-life in patients with advanced ischemic heart failure. doi.org/10.1093/stcltm…

This study assessed whether autologous bone marrow-derived mononuclear cells plus β-TCP added to the standard operative treatment for proximal humerus fractures (open reduction internal fixation) could reduce the incidence of secondary dislocations. doi.org/10.1093/stcltm…

Data points to ability of intratracheal administration of MSC-EVs to protect from oxidative stress, improve pulmonary epithelial function, and counteract development of fibrosis in a rat model of hyperoxia-induced bronchopulmonary dysplasia. doi.org/10.1093/stcltm…

Identifying surface markers that aid in enriching retinal progenitor cells (RPCs) capable of differentiating into cone cells is a complex task. This article reports a promising novel surface marker, Sstr2. doi.org/10.1093/stcltm…