A latest protocol describing the retrograde trafficking of cation-independent mannose 6-phosphate receptors (CI-M6PR) using a CD8α-CI-M6PR chimera. bio-protocol.org/en/bpdetail?id…

Work by shalini rawat and Mahak Sharma at IISER Mohali.
Reviewed by  AmbrogioLab.

Enjoy this protocol for assessing endosome motility 'CD8α-CI-M6PR Particle Motility Assay to Study the Retrograde Motion of CI-M6PR Receptors in Cultured Living Cells' bio-protocol.org/en/bpdetail?id…
Mahak Sharma
Amit Tuli
IISER Mohali
Bio-protocol

CD8-alpha-CI-M6PR Particle Motility Assay to Study the Retrograde Motion of CI-M6PR Receptors in Cultured Living Cells bio-protocol.org/en/bpdetail?id… shalini rawat Mahak Sharma IISER Mohali DBT/WT India Alliance Department of Biotechnology SERB Bio-protocol

We have an opening...do apply if you want to study #lysosomes and love doing #cell biology Chandigarh Smart City IISc Bangalore IISER Mohali IISER Pune Department of Biotechnology CSIR, India DSTIndia SERB ICMR PhD Scholarship #phd #phd life

Congratulations Athira Pushpakaran and all the authors.

What an enlightening seminar delivered by Dhruba Chatterjee from the lab of Samrat Mukhopadhyay ! 💡 Delved into the nuances of liquid-liquid phase separation, also explored the role of multivalency & impact of conc. on phase separation. #SeminarRecap #FUS #proteins #PhaseSeparation

Thrilled to share Michael's new story published in Cell: We identify a nutrient-regulated phosphoinositide switch that triggers the conversion between motile mTORC1 signaling-active anabolic and static mTORC1 signaling-inactive degradative lysosomes. authors.elsevier.com/sd/article/S00…

Want to know more about how the presynaptic compartment is formed and assembled in human neurons? Please see Sila's new paper form our lab just out in Science: DOI: 10.1126/science.adg1075.

Join us this Saturday to “Talk To A Scientist about Lysosomes'🦠🧹🧽
Get ready to 'digest' some science as we learn all about lysosomes with Dr. Mahak Sharma(Mahak Sharma) from IISER Mohali.
📆30th September 2023
⏰5 p.m. IST
Registration Link: shorturl.at/yBKN9

When your 'education' limits your imagination it's called indoctrination. Those who cannot think for themselves are truly lost.
Education should be a rewarding experience which allows you to think, imagine, question, doubt and solve problems.

'The value of a college education is not the learning of many facts but the training of the mind to think.'

-- A. Einstein (1879 - 1955)

#Hike_in_fellowship
It's time to step up and provide us the answer we deserve! We strongly urge a meeting of authorities with scholars for transparency, accountability and genuine resolutions. Together,we can foster a culture of innovation and respect. #Hike_in_fellowship

The measure of your intelligence is not your ability to acquire knowledge but how you handle uncertainty and navigate through it and behave when you don't know what to do.

Congratulations shalini rawat Mahak Sharma and team rupress.org/jcb/article/22… JCellBiol Dept. of Biological Sciences (DBS), IISER Mohali IISER Mohali Autophagy India Network (AIN) Shrestha shaw Indian National Young Academy of Sciences (INYAS) Department of Biotechnology SERB

#ResearchHighlight
A team led by India Alliance Senior Fellow Dr Mahak Sharma at the IISER Mohali has identified a new mechanism for the regulation of lysosomal function.
Dr Amit Tuli, CSIR-IMTech is also part of the research team.
Read more: indiaalliance.org/news/research-…

Exclusive #authorinterview with #biopatrika shalini rawat from @mahaksharma23 lab @IISERMohali talks about her work on 'RUFY1: A sorting station of endolysosomal system' published in JCellBiol. Collaborator: judith klumperman UMCU_CMM bit.ly/3UINPa2

Final year PhD students

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to #lysosomes , say shalini rawat @mahaksharma23 and colleagues @IISERMohali: bit.ly/3D4GTNO
🎥 See video summary by Rawat: youtu.be/u4kfnZXJz2s

Gaurav kumar khunger, Ph.D. Amit Tuli @csir_imtech

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.
doi.org/10.1083/jcb.20…

Another version of our recent video of the month in nature, capturing zebrafish embryo development #FluorescenceFriday #zebrafish #Microscopy (& thanks to napari🔬 animation plugin)