DOSIS - RCT in pts with painful vertebral mets
Hypothesis: improved LC -> durable pain response
First randomized trial with 6 mo pain reduction as prim endpoint
N=63 pts randomized to SBRT vs conv. RT
Significant benefit of SBRT: 69.4% vs. 41.9% (p=0.02)
doi.org/10.1002/cncr.3…

Martin Tom John Suh Cleveland Clinic MD MD Anderson Cancer Center Our residents are still raving about their time with the esteemed (& humble & kind & funny) John Suh today at MD Anderson Cancer Center

Thank you so much for taking your time to visit with us! (& sorry I had to watch your amazing grand rounds via zoom bc my consult clinic ran long!

“Management is doing things right; leadership is doing the right things” - Peter Drucker

Thank you John Suh Cleveland Clinic MD for coming as a VP to our #radonc program 🙏🏻

Your visit was filled w/ great 🌮 & conversation, CNS 🧠 clinical pearls, & fantastic leadership advice!

Wonderful catching up with my mentor and former chair John Suh Cleveland Clinic MD, here as visiting professor MD Anderson Cancer Center giving an incredible talk on his leadership journey.

Very honored to be a VP for the Department of Radiation Oncology ⁦MD Anderson Cancer Center⁩!! Truly appreciated the tour of the new proton beam facility, hospitality of the #radonc residents & faculty, discussion on leadership and opportunity to review some cases. ⁦ARRO⁩

This was one of the most fascinating guidelines I have been involved in. It shows how we need quality evidence to guide the integration of brain radiosurgery and targeted agents that can penetrate the blood brain barrier for brain metastases. pubmed.ncbi.nlm.nih.gov/38459978/

⁦Michelle Kim⁩ giving an amazing talk on RANO-RT at ⁦SNO⁩ Meeting.

Don't miss the deadline! Submit your abstracts for #ARS2024 by November 12! #radiationoncology #medicaloncology #surgicaloncology #CME #posters #oralpresentations
americanradiumsociety.org/page/2024annua…

Combining amino acid PET and MRI imaging increases accuracy to define malignant areas in adult glioma nature.com/articles/s4146…

Randomized study published in Lancet today, showing 62% EFS improvement with Nivo + SABR compared with SABR alone in early stage NSCLC. I-SABR is a promising TX option.

awbs://authors.elsevier.com/c/1hRV5V-4XL3dJ
IASLC
MD Anderson Cancer Center The Lancet Albert Koong, MD PhD
Stephen V Liu, MD

Official 2023 MD Anderson Cancer Center #radonc faculty group photo. Many new additions. Great to see so many faculty in person. #endcancer

A prospective study by Martin Tom and colleagues showed that PET/CT with 18F-fluciclovine, a repurposed widely available radiotracer, has promising ability to distinguish radiation necrosis from tumor progression after #radiosurgery .
Read more: link.springer.com/article/10.100…

This is a rather troubling study. The fact that it got published in NEJM is concerning, to say the least

Astonishing cost of $16 000/month for a drug administered continuously until disease progression in a trial with a dubious endpoint and flawed design

Here are my thoughts:

#ASCO23 PLENARY: Indigo RCT Improved PFS w/ Vorasidenib for IDHmutant low-grade glioma! nejm.org/doi/full/10.10…

Patients diagnosed with a #braintumor have more treatment options than ever thanks to the Brain and Spine Center MD Anderson Cancer Center Department of #Neurosurgery . Learn more about the types of brain tumors we treat: bit.ly/3fzDDQC
#GoGrayInMay #GrayMay #OncSurgery #EndCancer

#radonc faculty photo ⁦MD Anderson Cancer Center⁩. I am privileged to work with such a great group of dedicated faculty who deliver excellence in clinical care, research, and education everyday. #endcancer #gratitude ⁦Peter WT Pisters, MD⁩

Treating multiple brain mets w/SRS, how do you know if mean brain dose is safe?

Compared GK & CyberKnife platform w/4 sets lesion sizes prescribed 20 Gy

Pertinent ONGOING trial CE7:  5+brain mets SRS vs. HA-WBRT+memantine
mdpi.com/2095832 #mdpicancers via Cancers MDPI

Doctors at a major US insurance company deny tens of thousands of claims a month without even looking at patients’ files.

“We literally click & submit,” a former Cigna doctor told @ProPublica & The Capitol Forum. “It takes all of 10 seconds to do 50 at a time.”

The inside story 🧵

Salvage hypofractionated SRS is an increasingly utilized treatment option following failed SRS for brain metastases. A new article from Sunnybrook Health Sciences Centre shows that this therapy results in favorable control rates and toxicity rates. link.springer.com/article/10.100…

Finally a positive phase 3 study for patients with low grade glioma, who are often young at diagnosis.Will meaningfully delay chemo and RT! ⁦Lynne P. Taylor, M.D.⁩ ⁦Manmeet Ahluwalia, MD, MBA, FASCO⁩ ⁦Mustafa Khasraw⁩ ⁦MJ Lim-Fat⁩ ⁦Simon Lo⁩ ⁦ servier.us/serviers-pivot…