New paper out from the Mackall lab!! Tweetorial from Mackall Lab coming soon!

Beyond excited to share that my project from Mackall Lab and Stanford Medicine, led by my incredible postdoc-turned-PI Evan Weber, in collaboration with his new(ish) lab at Children's Hospital, is now published in Nature! Check it out here:

nature.com/articles/s4158…

Memory genes are enriched in CAR T cells that persist and control tumors in patients. But which transcription factors drive beneficial memory programs?

We answer this in our lab’s first paper in nature led by Alex Doan Kat Mueller, PhD Andy Chen. 1/

nature.com/articles/s4158…

🗣️wahoo!!! my doctoral work is out online in Cell: authors.elsevier.com/c/1ie1VL7PXqPm4!! couldn't have done it without my two wonderful labs and co-advisors Stanley Qi Lab & Mackall Lab

we developed a new RNA-targeting CRISPR platform (MEGA) to engineer better T cell therapies...🧵

Inosine makes CAR-T cells more stem-like and potent. It redirects their metabolism and reprograms their epigenome and transcriptome. An easy and feasible way to enhance CAR-T cell product potency at clinical scale! ✨💪🏻

Our latest work out in Cancer Cell.
#CART #immunometabolism #immunosuppression

Inosine induces stemness features in CAR-T cells and enhances potency sciencedirect.com/science/articl…

Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy dlvr.it/T17Bfc

Coming soon!🎙️Episode 3 of From Bench to Fireside™ on Spotify takes you from behind the lab bench to the frontiers of cancer research with immunotherapy pioneer Dr. Crystal Mackall Mackall Lab, PICI Center Director Stanford Medicine. Follow for updates: spoti.fi/47Iqc8Y

Another cool review paper idea:

What have we learned after all these single cell analyses? Not what we measured, but what we actually learned!

What was changed in biology text books due to single cell analysis?

We are hiring a lab manager/tech for the new lab at DFCI! Please apply or get in touch if interested! The job will be part management and part science - very flexible - careers.dana-farber.org/job/senior-res…

The 2023 edition of our annual special report on Women in Biopharma R&D is out! We tell the stories of 20+ incredible women who have made waves in the creation of new medicines — in many, many different ways

endpts.com/meet-20-women-…

Congratulations to Crystal Mackall, MD (Mackall Lab), Center Director of PICI Stanford Medicine, for being named to Endpoints News’ 2023 list of the top women leading #biopharma #R &D! #WIB23 #PICINetwork

x.com/ambertongpw/st…

Meet 2023 Parker Bridge Fellow Zinaida Good, PhD Zinaida Good Stanford Medicine. Her work is leading to defining a “therapeutic” CAR T cell in patients with #cancer . Hear her thoughts on advancing immunotherapy here: youtube.com/shorts/a9ev6bL…

#PICINetwork #CancerResearch

Humbled and grateful to be selected as a 2023 Bridge Fellow by the Parker Institute for Cancer Immunotherapy to push forward CAR T immunotherapy research. parkerici.org/the-latest/ecr…

So honored to receive this New Investigator Grant from #ChadTough ChadTough Defeat DIPG Foundation! Excited to embark on this journey to improve immunotherapies for DIPG patients!

Crystal Mackall Lab and I visited the Galician Center for Advance Therapies, where #CAR -T cells will be manufactured to cover the needs of #Galicia . Thank u Rocio, Alicia and Mariona ( #Galaria ) for welcoming us! I'm a proud Gallega thrilled to help with this visionary project.

Amazing keynote talk by Dr. Mackall today at the ⁦ASGCT⁩ meeting. Promising results with GD2-CART in patients with brain tumors and novel strategies to tackle the TME. More reasons to believe that CAR-T cells may be used for solid tumors! ⁦⁦Mackall Lab⁩

🚨 Big announcement
The Ramakrishna Lab will be opening Summer 2023 Stanford Medicine @SCI to enhance #CART #Immunotherapy in children.

We are hiring at multiple levels, including the below position. If interested, please reach out!
m.rfer.us/STANFORDEHMMEI

#AACR23

defended my phd last week!! 🥹 so much heartfelt gratitude to my co-mentors Stanley & Crystal, and Stanley Qi Lab Mackall Lab for everything through the years – looking forward to the next chapter!