A succinct review on management of hepatitis B reactivation. Risks and decision for prophylaxis are based on serologic status of patients and type of immunosuppressive therapy.
Helpful figure to guide decision making.

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The role of immunotherapy in the evolving landscape of HCC treatment in the context of liver transplant.
Promising use needs to be balanced with allograft rejection
Expert opinion suggest a minimal of 12-week washout, more data needed

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2 more from our Hep B elimination series journals.lww.com/cld/pages/coll…

-Elimination: journals.lww.com/cld/fulltext/2…

-Functional cure (Anna Lok):
3%–5% after 10 yrs of nucleos(t)ide analogs; 8%–14% after 3–5 years of 48-wks of peg interferon. Trials also discussed
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The most in-depth and interesting article on the evolution of the Cardio-Hepatology field, a truly unique relationship:

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See the entire series of History of Hepatology collection here:

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Check out two recently published articles on the advances in Hepaititis B and Hepatitis D treatments!

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Anuragh Gudur, MD Alexander Podboy, MD, DABOM explore the ever expanding field of endo-bariatric therapies in treating MASLD

Endo Balloon & Sleeve Gastroplasty nuances and efficacy expertly discussed

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Robert Fontana & colleagues Michigan Hepatology guide us through the challenging (& common) scenario of how to establish a diagnosis of DILI in patients on chemotherapy in a stepwise fashion

A case of PKI-associated cholestatic granulomatous hepatitis:

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Two interesting articles on infantile cholestasis

1. Renal lesion associations: journals.lww.com/cld/fulltext/2…

2. Biliary atresia case:
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Ahmad Anouti, MD BARE

CLD series is curated by our Guest Editors to bring articles together to capture intent of the series. journals.lww.com/cld/Pages/CLD-…

Check out the new content added to the 'Pregnancy and Liver Disease' series.
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Metabolic Disorders play an important role in modifying hepatitis B outcomes

From our upcoming 'Current Challenges in the Management of Chronic Hepatitis B Infection' series collection:

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Editor-in-Chief Dr. Joseph K. Lim's editorial ClinicalLiverDisease

Clinical Liver Disease: Legacy of innovation in hepatology education

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Check out this review and interview with the author on inpatient management of fluid overload in patients with decompensated cirrhosis.

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Arguments for serial monitoring over treatment initiation in chronic hepatitis B inactive carriers, immune-tolerant, and indeterminate phase patients.

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- Challenges in achieving WHO goal of HBV 'viral elimination' by 2030.
- Proposed strategy for 'viral elimination': universial screening, rapid linkage to care and expanded antiviral treatment criteria.

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Edoardo Giannini 🇮🇹 discusses hepatocellular carcinoma management, including:

- How changing epidemiology may impact HCC surveillance
- Affect of liver severity on treatment options: multiparametric therapeutic hierarchy
- HCC recurrence risk nuances

ow.ly/ibGn50QXURB

A case of colorectal cancer in a patient with PSC cirrhosis. A helpful case to delve into important medical and surgical considerations in risk stratifying patients before major nonhepatic surgeries.
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MASLD (associated with obesity and insulin resistance) increases the risk of adverse pregnancy outcomes

Yolanda (Georgia) Karachaliou, MD, MSc and colleagues outline the latest data and potential interventions for this emerging topic

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A concise review on intrahepatic cholestasis of pregnancy. journals.lww.com/cld/fulltext/2…

~ Bile acid > 40, risk of preterm labor and meconium-stained amniotic fluid. UDCA reduces the risk.
~ BA > 100, risk of still birth, early delivery is recommended at 36 weeks

A very helpful guide to contraception consideration in patients with chronic liver disease and liver transplant recipients, accompanied by an insightful interview with Monika Sarkar
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There may be a sunset on the horizon, however, we will ensure it is one to remember!

Your favorite liver educational platform will be reminiscing about its best content over the years, as well as publishing new cutting edge content through to the sunset!

Stay tuned