In patients with kidney failure on dialysis, dapagliflozin was well tolerated, was slightly dialyzable, and had non-accumulating pharmacokinetic properties ca. 2023 from CJASN #Nephpearls #NephJC

👉 pubmed.ncbi.nlm.nih.gov/37227937/

'As rates of kidney transplantation continue to rise, further focus on long-term graft and recipient survival will be necessary...' This Editorial discusses the need to investigate the complex physiology of kidney transplant recipients bit.ly/CJASN0479

deirdre.sawinski

Complicated herpes zoster is often treated with intravenous acycloviris, which is linked to AKI. This Editorial discusses a recent study that compared rates of AKI among adults who received antiviral treatments for herpes zoster bit.ly/CJASN0480

Raymond Hsu Diana Kwong

There is substantial variation in the proportional use of PD among patients on prevalent dialysis by country and region. This Editorial examines a study that assessed variations in automated PD prescriptions in the US bit.ly/CJASN0481

Rajnish Mehrotra UW Nephrology

Congratulations to Dr. Ryan Chan who is the first author to this important contribution to the CJASN Home Dialysis Series University Health Network

Vascular Access Considerations in Home Hemodialysis : Clinical Journal of the American Society of Nephrology journals.lww.com/cjasn/abstract…

There is a global interest in expanding home dialysis utilization amongst patients with ESKD. This article describes various vascular access options in HHD & what needs to be taken into consideration in the selection and care of this access bit.ly/CJASN0499

Ryan Chan

'To borrow a metaphor from the maritime world, if the kidneys are a ship, at this point in history, we are a little better off than the Titanic...' This Patient Voice article discusses the impact of changes to the kidney allocation system bit.ly/CJASN0478

Does cognitive decline occurs after AKI? This study found AKI was associated with lower 3MS scores and sTNFR-1 concentrations appeared to mediate a significant proportion of the risk of long-term cognitive impairment bit.ly/CJASN0473

Alp Ikizler

ASN Kidney Translations 🎙️ Covering articles from JASN, CJASN, and ASN Kidney360, this Podcast episode discusses the effect of pantoprazole on eGFR slope, antiviral medications for Herpes Zoster, & link between pediatric AKI in Uzbekistan and cough syrups bit.ly/KTPOD51424

Understanding plasma metabolome patterns in relation to changing kidney function in pediatric CKD is important for continued research. This study characterizes longitudinal plasma metabolomic patterns linked to eGFR and UPCR in this population bit.ly/CJASN0463

Awareness of kidney replacement therapies (KRT) is associated with greater home dialysis use. This study reports a newly developed KRT knowledge instrument with three domains having acceptable internal consistency, reliability, and validity bit.ly/CJASN0472

An estimated 6,000 to 9,000 undocumented immigrants in the US have kidney failure. This Perspective proposes that providing support for kidney transplantation in this population can benefit both the states and the patients bit.ly/CJASN0491

No previously validated patient-reported experience measures exist for those undergoing home dialysis. This study shows the Home Dialysis Care Experience survey is an informative tool to evaluate patient experience of care for home dialysis bit.ly/CJASN0429

Wael Hussein

The Mayo Imaging Classification was developed to predict the rate of disease progression in patients with ADPKD. This study shows that this classification demonstrated acceptable stability and generally predicted kidney failure and eGFR decline rate bit.ly/CJASN0427

Preterm birth can disrupt normal kidney development. This study found that preterm birth was a risk factor for adverse outcomes in a heterogenous cohort of children and adults with glomerular disease bit.ly/CJASN0475

Kim Reidy

Since 2019, the ACGME has steadily reduced program administration protected time in all internal medicine subspecialties. This study found program leaders estimated minimum necessary program administration times that exceeded the ACGME requirements bit.ly/CJASN0412

National and international policies on parental leave for physician trainees are inconsistent. This study found most nephrology fellows were unaware of parental leave policies and pregnancy/lactation accommodations, emphasizing need for improved awareness bit.ly/CJASN0486

PLA2R is the most common target antigen in primary membranous nephropathy. This study found in patients with PLA2R-associated membranous nephropathy, risk score incorporating inherited risk alleles & PLA2R antibody enhanced disease progression prediction bit.ly/CJASN0422

PD-related infection is a major concern that may result in hesitation to consider this as treatment. This Review describes the definition, epidemiology, risk factors, prevention, and treatment of PD-related infection bit.ly/CJASN0280

David W Johnson KM Yeoungjee Cho

Urinary stone disease is a prevalent condition linked to high recurrence risk. This study demonstrates that the use of preventive pharmacological therapy is associated with a lower risk of clinically significant recurrent episodes of urinary stone disease bit.ly/CJASN0428