Very proud to share our latest collaborative paper with Baker Group where we disclose the chemo- and regio-selective differential modification of cysteines on a native antibody; a first-in-class strategy! Led by the fantastic Steven Yong-Yi Yap! UCL Chemistry
pubs.rsc.org/en/Content/Art…

Antibody drug conjugates (ADCs) are all the rage, for good reason.

They're generating stellar efficacy results in clinic, though they're not perfect.

I looked through 40+ ADC companies founded after 2010 to see what each was trying to improve on and with what new approach. ⬇️

Great few days at World ADC hearing about the latest developments in the field of Antibody-Drug Conjugates and of course catching up with old friends 🔬🧑‍🔬

Look who is on Forbes 30 under 30 list in Hungary: our own postdoc ⁦Peter Szijj⁩ ! Congratulations 🎉

Szijj Péter - Forbes 30/30 | 2024 - Forbes.hu forbes.hu/lists/forbes-3…

Welcome to our new post-doc within the Chudasama and Baker groups Suman Manna, PhD!

Suman will be working on protein modification throughout his post-doc.

Looking forward to some exciting research ahead! 🧪

Vijay Chudasama

#research

To finish his PhD in style, Dr Mikesh Patel also got his research published in J. Am. Chem. Soc.! 📖 🧪

Well done Mikesh and all those involved! Vijay Chudasama Mike Porter Nafsika Forte Matt Dagwell UCL Chemistry

pubs.acs.org/doi/10.1021/ja…

🥳 Huge congratulations to the latest Baker group PhD grad! Dr Mikesh Patel! 🥳

Thank you to Matthew Powner and Dr Barnard for examining! Good luck for the future Mikesh! 🧪 #PhD #chembio

📢Welcoming Matt Dagwell to the group! Matt will be working on protein modification throughout his PhD. UCL Chemistry

Very pleased to announce
Yanbo Zhao's publication on Trifunctional Dibromomaleimide reagents in ChemBioChem. 🥼
ChemBioChem
UCL Chemistry

doi.org/10.1002/cbic.2…

📢Exciting new PDRA opportunity to join the Baker Group and investigate new biorthogonal reactions via untapped modes of reactivity. Further information linked below. Deadline 16/08/23. 🥼

jobs.ac.uk/job/DBM562/res…

🎉Huge Congratulations and Well Done to Dr. Yanbo Zhao for completing her Viva! 🎉Thanks to Prof. Tabor and Prof. Spring for examining. Good Luck for the future in Shanghai! 🧪⚗️🐼

📢Exciting new PhD opportunity to join the Baker Group and investigate new Bioorthogonal Click Reactions. Further information linked. Deadline 20/07/23. 🥼
findaphd.com/phds/project/i…

Massive Congratulations to Dr. Haque on passing your Viva! 🎉 Thanks to Nick Mitchell and Jim Anderson for examining . Best of luck for the future at GSK! 🥼🧪

Very pleased to announce Roshni Malde's publication on photodecarboxylations of various maleimides in EurJOC EurJOC. 🥼🔦Also huge appreciation to Yanbo Zhao and Luigia Salerno for their contribution UCL Chemistry
…mistry-europe.onlinelibrary.wiley.com/doi/full/10.10…

Adios Barcelona 🇪🇸👋

Something more familiar with our work - ADCs. A very nice systemic study into the effect of conjugation site and technique on ADC stability/PK. Nice work by Christian Schroeter Merck #PEGSEurope

Machine learning is everywhere - now in antibody discovery too. Nice insights by Oxford Protein Informatics Group (OPIG) into the work being done. A real pioneering effort. #PEGSEurope

Really useful breakout discussion. A lot of industry experts in the circle sharing their problems and ideas. #PEGSEurope