Summary of Autoantibodies in Rheumatology

by Mithu Maheswaranathan, MD
#medtwitter #foamed #rheumatology

Summary of Autoantibodies in Rheumatology

by Mithu Maheswaranathan, MD #MedEd #medx

Christopher Webb Bee Cee Geez Running Chris K. Sakys Mike Pence's Other Mother 🟧🟦🟪 THEE Gavin says seize Trump's properties LFG🌊 blacks4kennedy Vaccines have not been linked to causing Celiac. “…COVID-19 Vaccination Does Not Induce New-Onset Formation of Autoantibodies Typically Accompanying Lupus…Rheumatoid Arthritis, Celiac…and Antiphospholipid Syndrome.” ncbi.nlm.nih.gov/pmc/articles/P…

Study Shows Insights Of Nuanced Interactions Between Autoantibodies And Specific COVID-19 Symptoms With Anti-AGTR1 Antibodies Playing A Key Role

thailandmedical.news/news/study-sho…

#COVID19 #News #SARS CoV2 #SARS #America #USA #Autoantibodies #UnitedKingdom #France #Paris #Thailand #Sydney

Clinical studies targeting autoantibodies

While traditionally associated with autoimmune diseases, autoantibodies can also have protective roles. Understanding the complex interplay of autoantibodies in disease pathways offers opportunities for new treatment paradigms.

science.org/doi/10.1126/sc…

medicalxpress.com/news/2024-04-s…

'Anti-MDA5 antibody-positive dermatomyositis involves the production of autoantibodies against the protein MDA5, causing rashes, lung inflammation, and fibrosis, called interstitial lung disease (ILD).'

tern Nasty people. Saying to many autoantibodies and not enough antibodies. Blame the unvaccinated.

Shaney Wright Gerald Commissiong charlos autoantibodies man, autoantibodies, what’s your problem?

degruyter.com/document/doi/1…

'A subset of DM, notably amyopathic dermatomyositis in the absence of autoantibodies may be on the spectrum of autoinflammatory disease.'

'Currently, therapeutic regimens differ between DM and SAIDs.'

Why is daratumumab not in any Sjogrens trial? Daratumumab is a perfect candidate medicine because it handles what makes Sjogrens a beast: long lived plasma cells autoantibodies!

Autoantibodies were found to bind the following G protein-coupled receptors (GPCRs) in LC patients(3):
✅ β2-adrenoceptor
✅ α1-adrenoceptor
✅ angiotensin II AT1-receptor
✅ nociceptin-like opioid receptor

Once bound the autoantibodies prevent the receptor from working.

Autoantibodies to selenoprotein P in chronic fatigue syndrome suggest selenium transport impairment and acquired resistance to thyroid hormone

twitter.com/renesugar/stat…

💡 NEW RESEARCH Communications Medicine – Felton et al. review the evidence on islet autoantibodies as precision diagnostic tools for #T1DM heterogeneity | @emksims Jamie Felton Richard Oram Cate Speake Stephen Rich Dr. Carmella EvansMolina Dr. LA DiMeglio Heba Randi K Johnson
nature.com/articles/s4385…

Autoantibodies were found to bind the following G protein-coupled receptors (GPCRs) in LC patients(3):
✅ β2-adrenoceptor
✅ α1-adrenoceptor
✅ angiotensin II AT1-receptor
✅ nociceptin-like opioid receptor

Once bound the autoantibodies prevent the receptor from working.

researchers also examined blood samples from 100 patients & uncovered autoantibodies targeting Xist-associated proteins that scientists hadn’t previously linked to autoimmune disorders. A potential reason, Chang suggests: standard tests for autoimmunity were made using male cells

🔎 What serum autoantibodies(AAB) are assoc w/ CLAD?
💭Daniel Vousaghi at UGH Toronto investigates! 164 🫁♻️recipients in a case-control subset
🪣CLAD (n=61) and CLAD-free (n=100) @ 5 years
👀 AAB in CLAD and non-CLAD subjects.

Viruses | Free Full-Text | Autoantibodies to Interferons in Infectious Diseases mdpi.com/1999-4915/15/5…