Sense Receptor(@SenseReceptor) 's Twitter Profile Photo

'They unblinded everyone shortly after [the AstraZeneca trial], I'd say late February, March [of 2021]...It's supposed to be a double-blind study, but they unblinded everyone. It's like, 'Come on in if you want a shot'...that ruins the study right there.'

AstraZeneca

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Matt Lee(@wannabehawkeye) 's Twitter Profile Photo

Interesting paper from JAMA Surgery with relevance for . Quantifies placebo effect Vs real effect in blinded Vs unblinded trials of procedural interventions. PROMs & HCP assessed outcomes vulnerable.



doi:10.1001/jamasurg.2024.0718

Interesting paper from @JAMASurgery with relevance for #surgicalresearch.  Quantifies placebo effect Vs real effect in blinded Vs unblinded trials of procedural interventions. PROMs & HCP assessed outcomes vulnerable. 

#SoMe4Surgery

doi:10.1001/jamasurg.2024.0718
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Chris Carper(@mtheory11bio) 's Twitter Profile Photo

$ADXN with twice the average daily volume in the pre-market, perhaps investors are discovering that they have a good chance to show positive epilepsy data this quarter.

The interim review committee recommending to continue the study after seeing unblinded data is encouraging.

$ADXN with twice the average daily volume in the pre-market, perhaps investors are discovering that they have a good chance to show positive epilepsy data this quarter.

The interim review committee recommending to continue the study after seeing unblinded data is encouraging.
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Joan Crawford(@joan_crawford1) 's Twitter Profile Photo

Dr Annie Hickox Diane O'Leary, PhD FND is full of uncertainty and ambiguity. Humility and caution needed from all perspectives. Misdiagnosis, misunderstandings, misinterpretations, mis direction of correlation/causation, treatment EB based on subjective outcome measures in unblinded trials. Low quality. Etc.

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Not Quite Texas Proud(@texanfeminist23) 's Twitter Profile Photo

To be clear, if patients/providrrs can immediately or nearly immediately determine group assignment, it’s not considered blind. I’ve seen trials determined unblinded bc patients figured out the drug had a metallic taste. When half the group gets a beard they’re gonna know x.com/maccanorton/st…

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Nicolina(@Nicolina0815) 's Twitter Profile Photo

Safety and reactogenicity of the BNT162b2 COVID-19 vaccine: Development, post-marketing surveillance, and real-world data

ncbi.nlm.nih.gov/pmc/articles/P…

Funny! This study can't exist because 6 months after the start of the study, the study was unblinded and exactly 37 injected

Safety and reactogenicity of the BNT162b2 COVID-19 vaccine: Development, post-marketing surveillance, and real-world data

ncbi.nlm.nih.gov/pmc/articles/P…

Funny! This study can't exist because 6 months after the start of the study, the study was unblinded and exactly 37 injected
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Carole Lynn Servideo(@Hanksoso1) 's Twitter Profile Photo

The man who gave me my rescue pup wrote a book.
He became blind at age of 36 yrs. He is amazing. I keep in touch and give him reports. I can’t imagine the pain he suffers, giving up such a loving dog. His book is
Unblinded. We love you, Kevin.

The man who gave me my rescue pup wrote a book. 
He became blind at age of 36 yrs. He is amazing. I keep in touch and give him reports. I can’t imagine the pain he suffers, giving up such a loving dog. His book is
Unblinded. We love you, Kevin.
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Dan Clinton(@DanClintonRN) 's Twitter Profile Photo

AZT was approved b/c of 1 study that lasted just 24 weeks that functionally became unblinded b/c of the overt bone marrow suppression. It was then prescribed every four hours for life even though it caused neutropenia in 16% + transfusable anemia in 24%!
nejm.org/doi/full/10.10…

AZT was approved b/c of 1 study that lasted just 24 weeks that functionally became unblinded b/c of the overt bone marrow suppression. It was then prescribed every four hours for life even though it caused neutropenia in 16% + transfusable anemia in 24%!
nejm.org/doi/full/10.10…
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Taishi Okuno(@taishiokuno) 's Twitter Profile Photo

‘Faith Healing’ and ‘Subtraction Anxiety’ in Unblinded Trials of Procedures | Circulation: Cardiovascular Quality and Outcomes ahajournals.org/doi/10.1161/CI…

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Rodney Lauer(@LauerRodne91355) 's Twitter Profile Photo

A coincidence Time and Time again. So give this Truth from Hot Rod a read. Follow along and I'll show you Just how deep one burrow goes. If U pay real close attention you will be Unblinded by the Light I bring. Where can I find Mr Elon Musk? Let Us c.
Neo1
youtu.be/OnDu1HHOo78?si…

A coincidence Time and Time again. So give this Truth from Hot Rod a read. Follow along and I'll show you Just how deep one burrow goes. If U pay real close attention you will be Unblinded by the Light I bring. Where can I find Mr Elon Musk? Let Us c.
Neo1
youtu.be/OnDu1HHOo78?si…
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lae'zel quotes(@laezelquote) 's Twitter Profile Photo

You are the tastes of my tongue. You are the ground beneath me and the skies above. The one who gave significance to this trivial rock...and the one who unblinded me to a terrible truth: I had built my life on an empty foundation.

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PolyPid(@PolyPidLtd) 's Twitter Profile Photo

Today $PYPD announced the enrollment of the 200th patient to our SHIELD II study. The study is approx. half enrolled to the planned unblinded . results are expected in the second half of 2024

Today $PYPD announced the enrollment of the 200th patient to our #Phase3 SHIELD II study. The study is approx. half enrolled to the planned unblinded #InterimAnalysis. #Topline results are expected in the second half of 2024

#LayerByLayer #Sugical_Site_Infection #SSI
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