Sauna bathing activates a variety of beneficial stress response pathways and cellular repair mechanisms:

• NRF2
• Heat shock proteins
• IL-6

Some downstream effects:

• Reduced inflammation
• Autophagy
• New stem cells
• DNA damage repair
• Antioxidant effects

ーデトックス促進フードー

Nrf2というグルタチオンの合成を促進するデトックスに重要な遺伝子を活性化する食品を論文を参考に調べてまとめた。

1. ニンニク
2. ブロッコリースプラウト(オススメ)
3. 生姜
4. ウコン
5. クローブ
6. カイエンペッパー
7. シナモン
8. クミン
9. カルダモン
10. シソ…

Like sulforaphane

Moringa powder activates the Nrf2 pathway

Rhonda adds it to smoothies

Happy #InternationalWomansDayinScience from the NRF2 lab! 👩🏼‍🔬👩🏼‍🔬👩🏼‍🔬👩🏻‍🔬

Methylene blue may be one of the most powerful skin protecting compounds today.

-Mitigates UV damage from long term sun exposure
-Improves skin collagen production
-Upregulates antioxidant genes such as Nrf2
-Combats insults such as acne, psoriasis, and eczema
-Boosts skin…

It's Nrf2 week! Join us for Paul Robertson this Thursday.

Dandelion is a great herbal supplement for inflammation:

⬩ Shows neuroprotective effects against glutamate-induced oxidative damage, mediated by activating the Nrf2/HO-1 pathways in HT22 cells.

⬩ Inhibits the production of proinflammatory mediators, including COX-2, iNOS, NO,…

🫚JENGIBRE CONTRA ENFERMEDADES INFLAMATORIAS

✅Sus compuestos tienen efecto analgésico y antiinflamatorio inhibiendo las vías COX2 y LOX.

El efecto podría ser similar al de la familia de los AINE

También es antioxidante activando la vía Nrf2

Dentro hilo🧵👇

Black Maca: Ancient aphrodisiac & essential part of any vitality stack

- Boosts endocannibinoid signaling
- Boosts dopamine via MAO inhibition
- Protects against oxidative stress (via Nrf2)
- Mitochondrial biogenesis (via PGC-1α)

Black Maca in particular has also been shown…

🆕 Deuterium-Depleted #Water suppresses tumour through regulating expression of ROS-related genes. Review also indicated beneficial effects of DDW monotherapy in #cancer treatment. It needs to be investigated whether DDW affects the Keap1-Nrf2 signalling pathway.

Come join us this Thursday 4/4 for Sharon Baumel-Alterzon on the Nrf2 pathway in beta cells.

The NRF2 Lab at IIBM wishes you a merry Christmas and a happy New Year. After a well deserved rest, we will bring on more science in 2024! 🎄🎄

The results taken together indicated that PM2.5 resulted in the ferroptosis by causing iron overload through Nrf2/Hmox1 signaling pathway, which could account for the inflammation in microglia.
sciencedirect.com/science/articl…

My continued biological education

Fundamentals of Redox regulation in biology

Source: NOX, Mitochondria

Functions: Metabolism, Epigenetics (SIRT1, MLL), Transcription (NRF2, NFκB, HIF1), Protein translation/folding/degradation, Kinase signaling (ERK, p38, PI3K), Programmed…

It decreases cerebral infarct volume and neurological deficit scores, and involves regulation of the PI3K/PKB and Nrf2/NF-κB signaling pathways.

Now available the final version of our last article:

'Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness'

| published in Free Radical Biology & Medicine |

pubmed.ncbi.nlm.nih.gov/37858747/

El cáncer implica estrés oxidativo, el Nrf2, que es lo que activa mi antioxidante, es Crucial CONTRA el estrés oxidativo incluido el crecimiento, la progresión y la resistencia a la terapia del cáncer. La patente de activación del nrf2 más eficaz en el mundo, es el GNM-X. DM🙌

スルフォラファンはNrf2活性化作用を介し抗酸化ストレス作用、アセトアルデヒド代謝作用およびLPS/TLR4シグナル経路を阻害することで四塩化炭素およびエタノール投与により誘発されるアルコール肝線維症を改善する。
ci.nii.ac.jp/naid/500001499…

•WD ( #sugar & fat), induces #memory dysfunction & redox unbalance
•Nrf2 pathway is implicated in WD-linked frontal cortex alterations
•Limosilactobacillus reuteri prevents diet-linked #brain dysfunction
• #Probiotic reduces gut absorption of #fructose and its delivery to brain

Dive into the intricate world of NRF2 signaling: Explore the current landscape in #RedoxBiology and learn about the hurdles in identifying biomarkers. bit.ly/49ZJYgM