PRC2 is reported to bind RNA. Yet, genetic experiments have raised serious questions about their functional relevance. Our paper revisits the biochemical evidence supporting widespread PRC2-RNA interactions and finds that many of these do not occur in vivo.…

Gegen den Rechtsdrift:
Wir brauchen eine offene Gesellschaft!
Mein Beitrag heute Frankfurter Allgemeine faz.net/1.9452332?prem…

Excited to share our collaboration with ENCODE to map enhancer-gene regulatory interactions across the human genome!

We developed a new model that beats ABC by incorporating additional information on promoter class and enhancer-enhancer interactions.

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Out today in nature, we describe HHV-6 reactivation in T cells, including therapeutic CAR T cells. I’m so grateful to have worked with an all-star team during my time in the Ansu Satpathy lab that led to these findings. nature.com/articles/s4158… 1/n