New from the May issue—
Large-scale pan-cancer cell line screening identifies actionable and effective drug combinations, by Azadeh C. Bashi, Dr Elizabeth Coker, Krishna C Bulusu, Jerome T. Mettetal, Garnett Lab et al.
bit.ly/3V1ekd9
Wellcome Sanger Institute Oncology at AstraZeneca

New from the May issue—
Co-Clinical Trial of Novel Bispecific Anti- #HER2 Antibody Zanidatamab in Patient-Derived Xenografts, by Timothy DiPeri, MD, Funda Meric-Bernstam et al.
bit.ly/4c13gDR
MD Anderson Cancer Center

🎉Congratulations to the following scientists who have received the Princess Margaret Cancer Centre (PM) Research Awards, announced during our 13th annual retreat.

Drs. Trevor Pugh, Vuk Stambolic, Mohammad Mazhab-Jafari, Jillian Tsai, Raymond Kim, and Shane Harding

More below.

🏆 Translational Paper of the Year-Drs. Trevor Pugh, Raymond Kim, collaborated with Dr. David Malkin from SickKids
> doi.org/10.1158/2159-8…

Published in Cancer Discovery, this collaborative work applied a multimodal liquid biopsy for early cancer detection in Li-Fraumeni Syndrome.

FOMO!! And check out Ping Mu 🇺🇦's paper here 😃: doi.org/10.1158/2159-8…

You can read the review mentioned in the first picture inspired by the first #EMBOCancerEvo meeting here 😁aacrjournals.org/cancerdiscover… Enjoy the meeting everyone!!

And we’re starting!!! #TMEFOCE #EMBOCancerEvo #Rimini Giovanni Ciriello Luca Magnani Anna Obenauf with the PRC2 expert Adrian Bracken 🥳

Novel molecular insights regarding #Ventoclax resistance in #Leukemia and food for thoughts in eradicating LSCs/residual disease! Congrats to Jordan Lab and team! 🧬🧫🧑‍🔬

Less than 30 days away!

Just got the scoop at the #Myeloid2024 meeting! Now published! Amazing work as always from Jordan Lab

Ready for major FOMO to set in for both #EMBOcancerevo and #ASCO24 (at least attending the latter virtually) - but it’s for a good reason! 🧑🏼‍🎓

Now online in Cancer Discovery: Targeting Acute Myeloid #Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium - by Anagha Inguva Sheth, PhD Jordan Lab and colleagues doi.org/10.1158/2159-8… CU Anschutz Division of Hematology CU School of Medicine CU Anschutz Medical Campus #Venetoclax

CHD2 Regulates Neuron-glioma Interactions in Pediatric Glioma

Cancer Discovery AACR OncoAlert OncoDaily Columbia Medicine Herbert Irving Comprehensive Cancer Center Columbia Genetics and Development Department #MedEd #MedX #Oncology #cancerneuroscience

doi.org/10.1158/2159-8…

Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium

Cancer Discovery AACR OncoAlert OncoDaily Jordan Lab Anagha Inguva Sheth, PhD #MedEd #MedX #Oncology

doi.org/10.1158/2159-8…

Great collaborative research from Sihan Wu 吴思涵 lab about why small cell lung cancer #SCLC is sometimes so difficult to treat. Link below to take a deep dive into why. #relentlessdiscovery

Cancer Discovery News #NotedThisWeek : A curated list of recent breaking news.
bit.ly/4bPDrXi

Did u know the AACR Journals has simultaneous publication opportunities? Here's a picture of corresponding author Xin Zhou presenting his article that published at #AACR24 .
aacrjournals.org/cancerdiscover…

New from the May issue—
MYC #ecDNA drives acquired cross-resistance in #SCLC , by Shreoshi Pal Choudhuri, Michael Lawrence, Sihan Wu 吴思涵, Ben Drapkin et al.
bit.ly/3ywyZyb
Children’s Research Institute at UT Southwestern UTSW Simmons Cancer Center Mass General Cancer Center Broad Institute

Cancer Research aims to distinguish itself as the home of convergence science with content that will stimulate discussion and support the next series of discoveries within the field. Read some of the top articles in this section:
bit.ly/3UISHy8

Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis

Cancer Discovery Santi Demajo Meseguer abeldavidgp Nuria Lopez-Bigas bbglab @irbbarcelona CIBERONC

doi.org/10.1158/2159-8…